Rupenangshu Kumar Hazra

Biography

He is working as scientist at the Indian Council of Medical Research, India.

Research Interest

27 years of research experience in field of vector biology, control, Parasitology, molecular entomology and genetics of vector competence,Working on surveillance and epidemiology; ecology, biology, bionomics and control of mosquito vectors including integrated vector control; field evaluation of various insecticides, Development of filarial and malarial parasites in vectors. Studies on J.E. Vectors.Large scale production of filarial infective larvae in laboratory through membrane feeding techniques.Host-parasite-vector relationship, maintaining mosquito colonies and developmental stages of human filarial and malarial parasites in laboratory.Immunological and biochemical studies, invertebrate tissue culture and insect immunology.Virological isolation of CHIKV and Dengue from vector.Developed a new multiplex PCR for simultaneous identification of malaria vector and their vectorial attributes which is now in translational mode.Detection of Dengue type II and Type III mosquito during dengue outbreaks in Odisha.In Odisha Chikungunya caused by viral strains of (IOL) genotype, evolved from ECSA genotype with E1-A226V mutation, which in turn Ae. albopictus as main arboviral vector.Further analyses revealed that CHIKV in India grouped specifically into Indian subcontinent lineage having certain genetic variations. ECSA (IOL) genotype was observed from the E2 gene.All the CHIKV isolates (mosquito and serum) were closely had second step adaptive mutations E2- I 211E and L 210 Q, increasing the vectorial capacity of Ae. albopictusfor CHIKV transmission.