Dr. Sanjeev Shukla
Assistant Professor
Biological Sciences
Indian Institute of Science Education and Research, Bhopal
India
Biography
Assistant Professor (May 2013-): Biological Sciences, Indian Institute of Science, Education and Research (IISER) Bhopal Postdoctoral Fellow (March 2010-March 2013): National Cancer Institute, National Institutes of Health, Maryland, USA Postdoctoral Fellow (May 2009-Feb 2010): Georgetown University Medical Centre, Washington DC, USA Ph.D. (Nov 2003-Feb 2009): Advanced Centre for Treatment, Research and Education in Cancer (CRI-ACTREC), Navi Mumbai
Research Interest
Examination of DNA methylation mediated regulation of alternative splicing via modulation of reciprocal binding of CTCF and BORIS in cancer cells. Analysis of DNA binding proteins/ transcription factors and upstream pathways that are involved in regulation of alternative splicing Examination of role of cancer specific alternative spliced isoforms in tumorigenesis
Publications
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Ryan J Marina David Sturgill Marc A Bailly Morgan Thenoz Garima Verma Maria F Prigge Kyster K Nanan Sanjeev Shukla Nazmul Haque Shalini Oberdoerffer TET-catalyzed oxidation of intragenic 5-methylcytosine regulates CTCF-dependent alternative splicing EMBO J 2016 Sathiya Pandi Narayanan Smriti Singh Amit Gupta Sandhya Yadav Shree Ram Singh Sanjeev Shukla Integrated genomic analyses identify KDM1A’s role in cell proliferation via modulating E2F signaling activity and associate with poor clinical outcome in oral cancer Cancer Letters 2015
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Sathiya Pandi Narayanan Smriti Singh Sanjeev Shukla A saga of cancer epigenetics: linking epigenetics to alternative splicing Biochemical J 2017