Remya Raja
Bioinformatics
Institute of Bioinformatics (IOB)
India
Biography
Dr. Remya Raja obtained her Ph.D. degree from Pune University, Pune, India. She pursued her doctoral research in Dr. Gopal Kundu’s laboratory at National Centre for Cell Science, Pune where she was involved in delineating the molecular mechanisms through which osteopontin potentiates breast tumor growth and angiogenesis under hypoxic conditions. Following her Ph.D., she joined IOB as DBT postdoctoral fellow under Dr. Akhilesh Pandey. She is a recipient of Thermo Global Science Alliance Scholar award. During her postdoctoral tenure at IOB, she worked on identifying tobacco-induced signalling pathways in esophageal cancer using proteomic approaches. She is a recipient of Young investigator grant from DST and is presently using CRISPR/Cas9 and proximity-based biotinylation (BioID) system to investigate activated signaling pathways in cancer.
Research Interest
Genomics Proteomics Cancer Biology Cell Signaling
Publications
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Raja, R., Sahasrabuddhe, N. A., Radhakrishnan, A., Syed, N., Solanki, H. S., Puttamallesh V. N., Balaji S. A., Nanjappa V., Datta, K. K., Babu, N., Renuse, S., Patil, A. H., Izumchenko, E., Prasad, T. S., Chang X., Rangarajan A., Sidransky, D., Pandey, A., Gowda, H., Chatterjee, A. (2016). Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells. Oncotarget.
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Rajagopalan, P., Nanjappa, V., Raja, R. , Jain, A. P., Mangalparthi, K. K., Sathe, G. J., Babu, N., Patel, K., Cavusoglu, N., Soeur, J., Pandey, A., Roy, N., Breton, L., Chatterjee, A., Misra, N. and Gowda, H. (2016). How does chronic cigarette smoke exposure affect human skin? A global proteomics study in primary human keratinocytes.
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Radhakrishnan, A., Nanjappa, V., Raja, R., Sathe, G., Puttamallesh, V. N., Jain, A. P., Pinto, S. M., Balaji, S. A., Chavan, S., Sahasrabuddhe, N. A., Mathur, P. P., Kumar, M. M., Prasad, T. S. K., Santosh, V., Sukumar, G., Califano, J. A., Rangarajan, A., Sidransky, D., Pandey, A., Gowda, H. and Chatterjee, A. (2016). A dual specificity kinase, DYRK1A, as a potential therapeutic target for head and neck squamous cell carcinoma. Scientific Reports
