Dr. Balvinder Singh

Biography

Significant recognition: Awards, fellowships, international funding of distinction, technologies transferred/licensed etc.: DBT Overseas Associateship Award 2006-2007 Senior Research Fellow (1992-1995), Council of Scientific & Industrial Research, New Delhi. National Eligibility Test (CSIR-UGC), 1992. Graduate Aptitude Test Examination (GATE), 1991. Selected list of Publications and Patents: Kaur R, Ahuja S, Anand A, Singh B, Stark BC, Webster DA, Dikshit KL. (2008) Functional implications of the proximal site hydrogen bonding network in Vitreoscilla hemoglobin (VHb): Role of Tyr95 (G5) and Tyr126 (H12). FEBS Lett., 582(23-24):3494-500. Kapoor D, Kumar V, Chandrayan SK, Ahmed S, Sharma S, Datt M, Singh B, Karthikeyan S, Guptasarma P. (2008) Replacement of the active surface of a thermophile protein by that of a homologous mesophile protein through structure-guided 'protein surface grafting' Biochim Biophys Acta. 1784(11):1771-6. Saxena R, Kanudia P, Datt M, Dar HH, Karthikeyan S, Singh B, Chakraborti PK. (2008) Three consecutive arginines are important for the mycobacterial peptide deformylase enzyme activity. J Biol Chem. 283(35): 23754-64. Bachhawat N, Singh B. (2007) Mycobacterial PE_PGRS Proteins Contain Calcium-Binding Motifs with Parallel beta-roll Folds. Genomics Proteomics Bioinformatics. 5:236-41. Singh, B (2004) PepBuild: A web server for building structure data for a peptide/protein. Nucleic Acid Res., 32:W559-W561 Luthra-Guptasarma, M. & B. Singh (2004) HLA-B27 lacking associated beta2-microglobulin rearranges to auto-display or cross-display residues 169-181: a novel molecular mechanism for spondyloarthropathies. FEBS Lett., 575:1-8. Nandel, F.S., N. Malik, B. Sinqh and D.V.S. Jain (1999). Conformational structure of peptides containing dehydroalanine: Formation of beta-bend ribbon structure. Int. J. Quant. Chem. (Biophysics), 72: 15-23. Nandel, F.S., R. Verma, B. Sinqh and D.V.S. Jain (1998). Mechanism of hydration of urea and guanidium ion: A model study of denaturation of proteins. Pure &. Appl. Chem., 70: 659-664. Nandel, F.S., B. Sinqh & A. Saran (1992). Conformational structure of the tetrapeptide Boc-Aib-­Leu-Leu-Aib-OMe- the central fragment of the nonapeptide antibiotic Leucinostatin A. Int. J. Quan. Chem., 42:1669-79. Patent: NF No. 0215NF2006/IN Title: Creation of an active stable chimeric protein through transplantation of the entire active surface of a protein onto its structural homolog. Inventors: Divya Kapoor; Sanjay Kumar Chandrayan; Shubbir Ahmed; Swati Sharma; Manish Datt; Balvinder Singh; S Karthikeyan Application No. 2411DEC2006

Research Interest

Molecular Modeling and Simulations; Bioinformatics.