Dr. Manoj Raje
Microbial Technology
Institute of Microbial Technology
India
Biography
Dr. Raje’s work on maintenance of iron homeostasis has overturned the six decade paradigm of iron acquisition and release by cells. These findings are the key to understand the balance of host pathogen interactions in tuberculosis.
Research Interest
Cell Biology, Biophysics, Multifunctional proteins, iron metabolism, high resolution imaging.
Publications
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Chauhan, A.S., Manoj Kumar,M., Chaudhary, S., Patidar, A., Dhiman, A., Sheokand, N., Malhotra, H., Raje, C.I. and Raje, M. Moonlighting glycolytic protein glyceraldehyde-3-phosphate dehydrogenase (GAPDH): An evolutionarily conserved plasminogen receptor on mammalian cells.(2017).The FASEB Journal, Manuscript in Press: DOI10.1096/fj.201600982R Online Publication Date Issue 2017-06-01 Volume 31 Issue No.6.
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Sheokand N., S., Himanshu M., Santosh K. , Tillu,V.A., Anoop Singh Chauhan, A.S, Chaaya Iyengar Raje, C.I. and Manoj Raje, M. (2014). Moonlighting cell surface GAPDH recruits Apo Transferrin to effect iron egress from mammalian cells. Journal of Cell Science; 2014,127, 4279–4291.
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Sheokand, N., Malhotra,H., Chauhan, A.S., Kumar, M., Chaudhary, S. Patidar, A., Boradia, V.M., Raje, C.I., and Raje, M. Reverse overshot water-wheel retroendocytosis of Apo Transferrin extrudes cellular iron. (2016). Journal of Cell Science; 2016, 129, 843-853 doi: 10.1242/jcs.180356.