Pradip Kumar Mahapatra
Associate Professor
Department of Chemistry
Jadavpur University
India
Biography
Dr. Das had completed Ph.D in 2000 from University of Calcutta,Kolkata (S I N P).His specialization is Inorganic Chemistry.
Research Interest
1) On aspects of modifying or simplifying some established anticancer drugs for reasons of high cost and toxic side effects. 2) On aspects of complex formation that lead to reduction in cytotoxicity of different classes of compounds that are otherwise very useful either as industrial chemicals or in medicine. 3) On aspects of DNA interaction (including method building)of simple inorganic complexes, monitored by spectroscopic and electrochemical techniques in order to understand various mechanisms of drug action. 4) On aspects of radiosensitization by simple inorganic complexes on target nucleic acid bases or DNA or cells.
Publications
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Spectroscopic, computational and electrochemical studies on the formation of the copper complex of 1-amino-4-hydroxy-9,10-anthraquinone and effect of it on superoxide formation by NADH dehydrogenase. A study on the formation of the nitro radical anion by ornidazole and its significant decrease in a structurally characterized binuclear Cu(II)-complex: impact in biology. Synthesis, crystal structure, DNA interaction and in vitro anticancer activity of a Cu(II) complex of purpurin: Dual poison for human DNA topoisomerase I and II.
