James Chelliah
Faculty Fellow
Neuroscience Unit (NSU)
Jawaharlal Nehru Centre for Advanced Scientific Research
India
Biography
James Chelliah currently working as Faculty Fellow Neuroscience Unit (NSU) Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) Bangalore, India.
Research Interest
James Chelliah research interest include Neurobiology of syngap1 in synaptic function and Intellectual Disability.
Publications
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mGluR1 activity generates persistent, NMDA receptor-dependent, depression of hippocampal pyramidal cell excitability. Clement JP, Randall AD, Brown JB. EJN 2009 May 29:12, 2347-2362.
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Pathogenic SYNGAP1 mutations impair cognitive development by disrupting the maturation of dendritic spines. Clement JP, Aceti M, Creson TK, Ozkan ED, Shi Y, Reish NJ, Almonte AG, Miller B, Wiltgen BJ, Miller CA, Xu X, Rumbaugh G Cell 2012 Nov 09;151(4): 709-23.
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SYNGAP1 links the maturation rate of excitatory synapses to the duration of critical period synaptic plasticity. Clement JP, Ozkan ED, Aceti M, Miller CA, Rumbaugh G. Journal of Neuroscience 2013 Jun 19;33(25):10447-52.
