Rakesh K. Tyagi
Professor
Special Centre for Molecular Medicine
Jawaharlal Nehru University
India
Biography
Proctor, Jawaharlal Nehru University, 2011-2013 Professor at the ‘Special Center for Molecular Medicine’, Jawaharlal Nehru University, New Delhi, India. 2011 onwards Chairperson of ‘Special Center for Molecular Medicine’, 2007 to 2009. Associate Professor at the ‘Special Center for Molecular Medicine’, Jawaharlal Nehru University, New Delhi, India. 2005-2011 Assistant Professor at the ‘Special Center for Molecular Medicine’, Jawaharlal Nehru University, New Delhi, India. 2001 to 2005. NIH Visiting Research Fellowship at the University of Texas Health Science Center (UTHSCSA) to work on `Androgen Receptor gene expression and Ageing` 1998-2001. INSERM International Fellow, Paris, France, 1995-1997. Feinberg fellow of The Weizmann Institute of Science, Israel, 1993-1995
Research Interest
a) Molecular and Cellular Endocrinology b) Nuclear Receptors in Health and Disease c) Endocrine-related cancers (prostate and breast cancers)
Publications
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Chaturvedi NK, Kumar S, Negi S, Tyagi RK (2010) Endocrine disruptors provoke differential modulatory responses on Androgen Receptor and Pregnane & Xenobiotic Receptor: potential implications in metabolic disorders. Molecular and Cellular Biochemistry 345:291-308.
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Kumar S, Jaiswal B, Kumar S, Negi S and Tyagi RK (2010) Cross-talk between Androgen Receptor and Pregnane & Xenobiotic Receptor reveals existence of a novel modulatory action of antiandrogenic drugs. Biochemical Pharmacology 80: 964-976.
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Kumar S, Chaturvedi NK, Kumar S and Tyagi RK (2008) Agonist-mediated docking of androgen receptor onto the mitotic chromatin platform discriminates intrinsic mode of action of prostate cancer drugs. Biochimica et Biophysica Acta -Molecular Cell Research 1783:59-73. (Impact factor 5.2)