Samudrala Gourinath
Professor
School of Life Sciences
Jawaharlal Nehru University
India
Biography
July 2015 – present- professor, School of life Sciences, Jawaharlal Nehru University, New Delhi-110067, India. 2016 – Guest faculty, Department of Biotechnology, South Asian University, New Delhi 2012-July 2015. Associate professor, School of life Sciences, Jawaharlal Nehru University, New Delhi-110067, India. 2003- 2012. Assistant Professor, School of life Sciences, Jawaharlal Nehru University
Research Interest
Structural and Functional studies of crucial pathway enzymes / proteins from E. histolytica & H. pylori i) Cysteine Biosynthetic pathway, sulfur metabolism in E. histolytica ii) Crucial signaling and cytoskeletal proteins involved in Phagocytic cup formation in E. histolytica iii) Replication initiation proteins from H. pylori.
Publications
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3. Sanjeev Kumar, Saima Aslam, Mohit Mazumder, Pradeep Dahiya, Aruna Murmu, Babu A. Manjasetty, Rana Zaidi, Alok Bhattacharya and S. Gourinath (2014) Crystal Structure of Calcium Binding Protein-5 from Entamoeba histolytica and its involvement in initiation of phagocytosis of human erythrocytes. PLoS Pathogens. 10(12):e1004532.
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2. Preeti Pandeya,b, Khaza Faisal Tariquea, Mohit Mazumdera, Syed Arif Abdul Rehmana, Nilima kumarib and S. Gourinath. (2016) Structural insight into ß-Clamp binding site in DNA Ligase of Helicobacter pylori. Scientific Reports. 6:31181
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1. S Dharavath, I Raj, S Gourinath (2017) Structure-based mutational studies of O-Acetylserine Sulfhydrylase reveal the reason for the loss of cysteine synthase complex formation in Brucella abortus. Biochemical J. BCJ20161062
