Uttam K. Pati
Professor
School of Biotechnology
Jawaharlal Nehru University
India
Biography
Uttam K. Pati has worked as: 2006-2007 Dean, School of Biotechnology. 2005- 2006 Chairman, Centre for Biotechnology. 2002 Professor. 1999 - 2001 Chairman. 1998 Acting Director, , JNU, Genetic Engineering Unit. 1994-2002 Associate Professor. 1990-1994 Assistant Professor of Medicine & Molecular Biology, School of Medicine, Augusta, Georgia, USA. 1986-1990 Associate Research Scientist, Yale University School of Medicine, CT, USA. 1983-1985 Research Associate, Yale University, CT, USA. 1982-1983 Research Associate, Massachusetts Inst. of Technology, Cambridge, USA. 1981-1982 Post doctoral Research Fellow, Max-Planck Inst, Germany. 1976-1978 Lecturer in Chemistry, Regional College of Education, Bhubaneswar.
Research Interest
Uttam K. Pati research interest include Molecular chaperones and gene regulation, Tumor suppressor proteins and their role in tumor regression, Molecular mechanism of Hypoxia and apoptosis , Biomarkers.
Publications
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3. R Gogna, E Madan, P Kuppusamy, U Pati. P53 core domain modifications determine apoptotic and necrotic death in cancer cells.Antioxidant & Redox Signaling, 16, 400-412, 2011. (2011 (doi: 10.1089/ars.2011.4103)
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2. R Gogna, E Madan, P Kuppusamy, U Pati. Re-oxygenation causes hypoxic tumor regression through restoration of p53 wild type conformation and post-translational modifications, Cell Death & Disease 3, e286; doi:10.1038/cddis.2012.15 & 2012 Macmillan Publishers Limited
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1. Esha Madan, Rajan Gogna, Periannan Kuppusamy, Madan Bhatt, Abbas Ali Mahdi, Uttam Pati. SCO2 Induces p53-Mediated Apoptosis by Thr845 Phosphorylation of ASK-1 and Dissociation of ASK-1-TRX Complex. Mol. Cell. Biol. doi:10.1128/MCB.06798-11, 2013
