Dr. Gopal Singh Bisht
Assistant Professor
Pharmacy
Jaypee University of Information Technology
India
Biography
Dr. Gopal Singh Bisht has joined Jaypee University of Information Technology as Assistant Professor (Grade-II) in Feb 2010. He is trained and experienced organic chemist with 6 years of post Ph.D. experience in research. Before joining JUIT, he worked as a Research Scientist at Ranbaxy research Laboratory, where he was responsible for design and synthesis of generic or new drug and their process optimization for scale up from the R and D Laboratory scale to the Manufacturing Plant scale. Dr. Bisht has carried out his Ph.D. work at Institute of Genomics and Integrative Biology (CSIR), where he worked on synthesis and biological evaluation of antimicrobial peptides and got his Ph.D. in Chemistry from University of Delhi, New Delhi, India, He has published his research work in peer reviewed journals such as BBA Biomembrane, Bioorganic and Medicinal Chemistry Letters, Chemical Biology and Drug Design, the FEBS Journal, Current Pharmaceutical Design. His current research focuses on design and synthesis of Peptides, Peptidomimetics and Heterocyclic compounds as antimicrobial and anticancer agents. He is also interested in natural product chemistry.
Research Interest
Synthesis of small molecules and peptidomimetics as lead antimicrobial compounds Synthesis of peptides, peptoids and heterocyclic peptide conjugates as anticancer agents Phytochemical Investigation of important Medicinal plants
Publications
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Sandeep Lohan, Swaranjit Singh Cameotra, Gopal Singh Bisht (2014). Antibacterial evaluation of structurally amphipathic, membrane active small cationic peptidomimetics: Synthesized by incorporating 3-amino benzoic acid as peptidomimetic element. European Journal of Medicinal Chemistry, 183 (), 102-115. Google Citation
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Sandeep Lohan, Arneesh Kalanta, Praveen Sonkusre, Swaranjit Singh Cameotra, Gopal Singh Bisht, (2014). Development of novel membrane active lipidated peptidomimetics active against drug resistant clinical isolates. Bioorganic and Medicinal Chemistry, 22 (17), 4544-4552. Google Citation
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Sandeep Lohan, Jitender Monga, Swaranjit Singh Cameotra, Gopal Singh Bisht (2014). In vitro and in vivo antibacterial evaluation and mechanistic study of ornithine based small cationic lipopeptides against antibiotic resistant clinical isolates. European Journal of Medicinal Chemistry, 88 (17 December 2014), 19-27. Google Citation
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Sandeep Lohan, Jitender Monga, Chetan Singh Chauhan, Gopal Singh Bisht (2015). In Vitro and In Vivo Evaluation of Small Cationic Abiotic Lipopeptides as Novel Antifungal Agents. Chemical Biology and Drug Design, (Forthcoming), -. Google Citation
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Sandeep Lohan, Jitender Monga, Chetan Singh Chauhan, Gopal Singh Bisht (2015). In Vitro and In Vivo Evaluation of Small Cationic Abiotic Lipopeptides as Novel Antifungal Agents. Chemical biology & drug design, 86 (4), 829-836. Google Citation
