Aparna Khanna
Dean
Life Sciences
Narsee Monjee Institute of Management and Higher Studies
India
Biography
Dr. Aparna Khanna is a Dean of Life Sciences Division at NIMS Institute. She received PhD in University of Mumbai . Dr. Aparna Khanna had 20 years of teaching experience. She had published 40 peer-reviewed research papers and written 2 Book Chapters. She had industry experience of about 8 years. She had patents on Pluripotent embryonic like stem cells derived from corneal limbus, method of isolation and uses thereof. (2006), Establishment of a human embryonic stem cell line using mammalian blastocysts (2006), In vitro assay methods for classifying embryotoxicity of compounds (2007),Methods of Characterization of Mammalian Embryonic stem cells by Multiplex PCR (2009), A Method Of Obtaining Mesenchymal Stem Cells, Medias Method And Composition Thereof (2010). Dr Khanna’s doctoral work involved molecular and cellular characterization of the hepatitis C virus (HCV) and development of an immunodiagnostic assay using the capsid protein of HCV. Her post-doctoral work included the characterization of Indian isolates of HCV and mapping the immunodominant region of the HCV envelope protein using synthetic peptides. Her current focus of research is design of novel nanoparticles for stem cell tracking, miRNA regulation and role in stem cell differentiation and scaffolds and biomaterials for tissue engineering, in the stem cell area.
Research Interest
Hepatoprotective activity of phytoextracts, nanoparticles for stem cell tracking, Hepatitis C virus
Publications
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Three dimensional polymer scaffolds for enhanced differentiation of human mesenchymal stem cells to hepatocyte-like cells: A comparative study
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Taparia SS, Khanna A. Procyanidin-rich extract of natural cocoa powder causes ROS-mediated caspase-3 dependent apoptosis and reduction of pro-MMP-2 in epithelial ovarian carcinoma cell lines. Biomedicine & Pharmacotherapy. 2016 Oct 31;83:130-40.
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Dutta S, Khanna A. Aglycone rich extracts of phytoestrogens cause ROS-mediated DNA damage in breast carcinoma cells. Biomedicine & Pharmacotherapy. 2016 Dec 31;84:1513-23.