Prashant Suresh Kharkar
Associate Professor
Pharmacy
Narsee Monjee Institute of Management and Higher Studies
India
Biography
Prashant Suresh Kharkar has long standing professional experience of 13 years. He was Drug discovery professional with expertise in Medicinal Chemistry and Computer-aided Molecular Design (CAMD) and Molecular Modeling. Managed discovery projects (metabolic disorders, cancer, pain, inflammation) in the lead identification and optimization stages. Managed interactions with team members from other disciplines & delivered all project goals in time. Currently working with SPP School of Pharmacy and Technology Management as Associate Professor, Department of Pharmaceutical Chemistry. He authored several publications in national and international journals. He has written 4 book chapters and have 2 government funded projects.
Research Interest
Pharmaceutical Chemistry, Process Chemistry, Excipient Chemistry, Synthetic Medicinal Chemistry, Computer-Aided Molecular Design
Publications
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Ghosh B, Antonio T, Zhen J, Kharkar P, Reith ME, Dutta AK. Development of (S)-N 6-(2-(4-(Isoquinolin-1-yl) piperazin-1-yl) ethyl)-N 6-propyl-4, 5, 6, 7-tetrahydrobenzo [d]-thiazole-2, 6-diamine and Its Analogue as a D3 Receptor Preferring Agonist: Potent in Vivo Activity in Parkinson’s Disease Animal Models. Journal of medicinal chemistry. 2009 Dec 28;53(3):1023-37.
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Kharkar PS, Warrier S, Gaud RS. Reverse docking: a powerful tool for drug repositioning and drug rescue. Future medicinal chemistry. 2014 Mar;6(3):333-42.
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Kharkar PS, Desai B, Gaveria H, Varu B, Loriya R, Naliapara Y, Shah A, Kulkarni VM. Three-dimensional quantitative structure− activity relationship of 1, 4-dihydropyridines as antitubercular agents. Journal of medicinal chemistry. 2002 Oct 24;45(22):4858-67.
