Usha Ghosh
Associate Professor
Chemical Engineering
Narsee Monjee Institute of Management and Higher Studies
India
Biography
Dr. Usha Ghosh has successfully executed 6 projects in the area of Cancer, Pain & Inflammation till the various stages of clinical developments. She was heading team involved in design and synthesis of NCEs based on mechanism of action for cardiovascular, immunology, anticancer and anti-inflammatory indications at Piramal Enterprise Limited. She had worked with Roche Product Limited for the process development of Vitamin-A production, troubleshooting in each stage of production and finally achieved the production of Vitamin-A palmitate free from its methyl ester and also worked on process development of few APIs involving enzymatic resolution and fine chemicals. At Sun Pharmaceutical Advanced Research Centre, Akota Road, Baroda, India synthesized nonapeptide, Leuprolide a LH-RH analog using solution phase chemistry. Worked on the process development of an antidepressant drug. She has taught undergraduate and postgraduate students and guided Ph. D. students in Pharmaceutical Research. She is having mentoring/motivating capability to students and group members for best results and outputs. She has been trained specifically for the issues related to safety in chemical laboratories.
Research Interest
Synthetic organic, organometallic, process, medicinal and polypeptide chemistry
Publications
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Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2016 Jan 2;12(1):1-222.
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Fleming I, Ghosh U. Synthesis of acylsilanes from amides and esters, and the selective oxidation of α-silyl alcohols to aldehydes. Journal of the Chemical Society, Perkin Transactions 1. 1994(3):257-62.
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Ghosh U, Ganessunker D, Sattigeri VJ, Carlson KE, Mortensen DJ, Katzenellenbogen BS, Katzenellenbogen JA. Estrogenic diazenes: heterocyclic non-steroidal estrogens of unusual structure with selectivity for estrogen receptor subtypes. Bioorganic & medicinal chemistry. 2003 Feb 20;11(4):629-57.
