Girish K Radhakrishnan

Biography

Education and training: Dr. Girish K. Radhakrishnan obtained MSc in Microbiology (1999) from School of Biosciences, Mahatma Gandhi University, Kerala and PhD in Biotechnology (2006) from School of Biotechnology, Madurai Kamaraj University, Tamil Nadu. He did his postdoctoral research (2006-2010) at the University of Wisconsin-Madison, USA and worked as Research Assistant Professor at the same university (2010-2012). He joined NIAB on 03 December 2012. Research experience and interests: Dr. Radhakrishnan has extensive research experience in the field of microbiology, immunology and protein chemistry. During his tenure at the University of Wisconsin-Madison, Dr. Radhakrishnan worked on the intracellular bacterial pathogen, Brucella melitensis. He studied the mechanisms by which B. melitensis modulates the host immune responses for its chromic persistence in the host. His research work revealed the molecular mechanism of suppression of Toll-like Receptor-2/4 signalling by the Brucella virulence protein, TcpB. At NIAB, he is studying the virulence determinants and immune evasion/suppression strategies of Brucella using various genomics and proteomics approaches with the objectives of developing efficient preventive strategies and diagnostic tools for brucellosis. He is also studying the intrinsic cellular processes that regulate innate immune responses in eukaryotes in the context of host-pathogen interactions. Selected awards, honours and fellowships: Post-doctoral Research Fellowship from University of Wisconsin-Madison, USA (2006-2010) CSIR-Junior Research Fellowship-NET in 1999 Travel grant by USA-Israel Binational Agricultural Research & Development Fund to attend a workshop on ssDNA viruses at Eilat, Israel, 2005 University Second Rank in MSc & College First in BSc.

Research Interest

Dr. Radhakrishnan has extensive research experience in the field of microbiology, immunology and protein chemistry. During his tenure at the University of Wisconsin-Madison, Dr. Radhakrishnan worked on the intracellular bacterial pathogen, Brucella melitensis. He studied the mechanisms by which B. melitensis modulates the host immune responses for its chromic persistence in the host. His research work revealed the molecular mechanism of suppression of Toll-like Receptor-2/4 signalling by the Brucella virulence protein, TcpB. At NIAB, he is studying the virulence determinants and immune evasion/suppression strategies of Brucella using various genomics and proteomics approaches with the objectives of developing efficient preventive strategies and diagnostic tools for brucellosis. He is also studying the intrinsic cellular processes that regulate innate immune responses in eukaryotes in the context of host-pathogen interactions.