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Microbiology Experts

Hemanta Koley

Scientist D
Bacteriology
National Institute of Cholera and Enteric Diseases
India

Biography

After completion of his Master degree in Physiology from University College of Science & Technology, Calcutta University, he joined in National institute of Cholera and Enteric Diseases, Beliaghata, Calcutta for his Ph. D. degree under super guidance of Dr. GB Nair. In 1996, he joined as Associate Professor in Dept. Physiology, College of Medical Sciences-Nepal, where he devoted entire heartily in teaching medical students till 2001. In the mean time Dr. Koley got opportunity for Post Doctoral research at Dept of Physiology, Rutgers -The State University of New Jersey, New Brunswick, USA. After completion of one year in Rutgers University, Dr. Koley moved to Boston, joined in Gastroenterology Section, Harvard Medical School as Research Associate and worked there on "Molecular mechanism of Barrett's esophagus and to identify therapeutic target for Adenocarcinoma" under leadership of Prof. R K Goyal, renowned gastroenterologist. Research Achievement: He has published 34 original papers and 25 abstracts in his credit. He has secured patent for a process for the preparation of Cholera Vaccine-VA1.3 (European Patent Office; Patent No.- 97309957.5-2105 on 19/05/98). Dr. Koley received Young Scientist Award in IUPS International Congress, Christchurch, New Zealand, August 2001. Invited Oration Lecture: "Dr. ( Mrs.) Chitralekha Mukherjee Memorial Oration-2010" at St. John's Medical College, Bangalore on 16th December 2010

Research Interest

His present research interest is to understand signal transduction pathways in immune and inflammatory cells during diarrhoea and also to study the nature of protection against diarrhoeal pathogens like Vibrio cholerae and Shigella in different animal model.

Publications

  • Mukherjee P, Raychaudhuri S, Nag D, Sinha R, Howlader DR, Mukhopadhyay AK, Koley H. 2016. Evaluation of immunogenicity and protective efficacy of combination heat-killed immunogens from three entero-invasive bacteria in rabbit model. Immunobiology. 221:918-26.

  • Mondal A, Tapader R, Chatterjee NS, Ghosh A, Sinha R, Koley H, Saha DR, Chakrabarti MK, Wai SN, Pal A. 2016. Cytotoxic and inflammatory responses induced by outer membrane vesicle-associated biologically active proteases from Vibrio cholerae. Infect Immun. 84:1478-90.

  • Mitra S, Sinha R, Mitobe J, Koley H. 2016. Development of a cost-effective vaccine candidate with outer membrane vesicles of a tolA-disrupted Shigellaboydii strain. Vaccine 34:1839-46.

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