Mahendra Seervi
Assistant Professor
Department of Biotechnology
Patna University
India
Biography
In 2014, he joined Patna Science College (Patna University) as assistant professor under DBT IPLS program. Currently he is pursuing many independent and collaborative projects to find novel compounds and model systems to study the mechanism and prevention of neurodegenerative disease and enhancement of lifespan. He is also exploring novel methods to remove Arsenic toxicity in human population using C.elegans as model system
Research Interest
Exploring cell death mechanisms Biotechnology
Publications
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Joseph J, Seervi M, Sobhan PK, Retnabai ST. High throughput ratio imaging to profile caspase activity: potential application in multiparameter high content apoptosis analysis and drug screening. PLoS One. 2011 May 27;6(5):e20114.
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Sobhan PK, Seervi M, Deb L, Varghese S, Soman A, Joseph J, Mathew KA, Raghu G, Thomas G, Sreekumar E, Manjula S. Calpain and reactive oxygen species targets Bax for mitochondrial permeabilisation and caspase activation in zerumbone induced apoptosis. PloS one. 2013 Apr 9;8(4):e59350.
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Joy B, Sivadasan R, Emilia AT, John M, Sobhan PK, Seervi M. Lysosomal destabilization and cathepsin B contributes for cytochrome c release and caspase activation in embelinâ€induced apoptosis. Molecular carcinogenesis. 2010 Apr 1;49(4):324-36.
