Vivek Lonkar
Management Cadre R&D at Serum Institute of India,
Medicine
Serum Institute of India
India
Biography
Management Cadre(Executive Officer) Company Name Serum Institute of India Limited Dates Employed Jun 2012 – Present Employment Duration 5 yrs 4 mos Location Pune  Vaccine R&D,production, Biotransformation & Conjugation (polysaccharide & protein), formulation.  Develop and improve purification & conjugation processes for microbial antigen (Protein & Polysaccharide) products (Down Stream Process, Molecular Biology).  Pneumococcal, Meningococcal A & Hepatitis B vaccine production (Upstream & Downstream).  Review of preparation, maintenance & updation of the regulatory documents, assessment of their compliance with regulatory norms of national & international regulatory bodies.  Protein & Conjugated protein analysis.  Molecular Biology approaches to improve protein & polysaccharide expression.  Small molecules pathway gene expression in Yeasts & Prokaryotes.  Gene disruption & integration.  Hypotheses for missing enzymes in Yeasts & Prokaryotes. Early Stage Researcher/ Research Technologist Company Name Praj Industries Ltd., Matrix The Innovation Center Dates Employed Apr 2009 – Jun 2012 Employment Duration 3 yrs 3 mos Location Pune Area, India  Strategic R&D, Product, facility development decisions Responsible for project proposal(discerning the need for prospective microorganisms, Metabolic engineering of microbes to develop proprietary strains (through rational & random mutagenesis, adaptation etc. strategies) & execution.  Project planning, management & execution, with mid level management. Mentoring & nurturing the team, annual formulation and day to day administration of the department and its facilities.  Upstream & Downstream process development.  Review of isolation, maintenance & preservation the microbiological cultures.  Process development for ethanol/butanol production (Standardization of optimum fermentation conditions) from various feed stocks (Artificial Media, Lignocelluloses, Corn, and Molasses), Method development for microbiological Assays of mutant selection.  Fermentation follow up (partial chemical fingerprinting through HPLC, GC) and other chemical analyses.  Simultaneous Saccharification Fermentation.  Metabolic Engineering.  Training & on site assessment of management tools.
Research Interest
Pharmaceutical company
