Dr. Lissy K. Krishnan

Biography

Academic Qualifications M.Sc in Biochemistry, University of Pune, 1977 Ph.D in Biochemistry, SCTIMST, 1990 Post Doctoral (Platelet Biology), University of Minnesota, 1990-92 Professional Record Product Development : i. Fibrin Glue (fibrinogen concentrate & thrombin), FVIII, as per EP specifications ii. Antibodies against viper venom as per WHO requirements iii. Fibrin Sheet as hemostat iv. Fibrin Wafer for Drug Delivery Research: i. Design of fibrin-based, cell-specific extra cellular matrix composition for differentiation of circulating adult stem cells for regenerative therapy (Endothelial cell, Smooth muscle cells, Neurons & Keratinocytes). ii. Development of hybrid scaffold using biodegradable polymer and biomimetic fibrin composite for: 1. Vascular graft tissue engineering 2. Skin tissue engineering Testing Service (ISO10993 part4) : i. In vitro blood compatibility & ii. In vitro drug response to vascular cells iii. Consultancy (free) provided for Industrial and Academic customers 4. Teaching: i. Initiated and coordinates M.Phil program of the Institute ii. Teach & Guide Ph.D. students iii. Class room teaching subjects: 1. Blood compatibility of biomaterials 2. Tissue Engineering 3. Adult Stem cells for regenerative Medicine

Research Interest

Development of tissue engineered small diameter vascular graft and tissue engineered skin substitutes using biodegradable hybrid (polymer-ECM) scaffolds; Standardization of technology for isolation/expansion/differentiation of autologous stem cells for patient-specific tissue engineering and regenerative purposes.