Krishanu Ray
Professor
Department of Biological Sciences
Tata Institute of Fundamental Research
India
Biography
Dr. Krishnau Ray is a Professor at the Department of Biological Sciences , TIFR. His focus is mainly on Molecular motors that are important for every possible regulated movement inside a cell.He focuses on understanding the logistics of this transport at the cellular and molecular level in appropriate biological contexts using Drosophila melanogaster as a model system. He has identified the molecular basis of cargo-motor interactions involving the tail domains of a unique heterotrimeric motor protein called, Kinesin-2. Currently we are in the process of identifying the use of these interactions in establishing the synaptic connectivity in the larval ganglion. He is also engaged in studying the effects of sensory stimulation on intracellular transport carried by Kinesin-2. A part of the lab is also studies the molecular cell biology of transit amplification divisions in Drosophila testis. In a recent development, we have stumbled upon a new phenomenon of reactive F-actin dynamics involved in preventing mechanical penetration of an epithelial cells.
Research Interest
Cell biology of motor proteins in Drosophila.
Publications
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Kulkarni A, Khan Y and Ray K (2016) Heterotrimeric Kinesin-2 together with Kinesin-1 contribute anterograde bias to the Acetylcholinesterase transport in axons. FASEB J
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Dubey P, Joti P, and Ray K (2016) A conditional Orco requirement in the somatic cyst cells for maintaining spermatids in a tight bundle in Drosophila testis. Journal of Bioscience 2 pp:1-11.
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Dubey P, Shirolikar S and Ray K (2016) Localized, Reactive F-actin Dynamics Prevents Abnormal Somatic Cell Penetration by Mature Spermatids Developmental Cell 38 pp: 507–521.
