Molecular Biology

Molecular Biology Experts

Dr. Philip Bentley

Advisory Council


Philip Bentley is currently Principal Consultant at Toxicodynamix International LLC. He spent 35 years working for Ciba-Geigy, later Novartis Pharmaceuticals where he held various management positions with responsibility for Investigative Toxicology; Drug Metabolism; Drug Metabolism and Toxicology; Preclinical Safety Europe; Drug Metabolism and Pharmacokinetics; Toxicology/Pathology USA; Preclinical Safety USA and Global Preclinical Safety. In these positions he had responsibility for various preclincal aspects of drug discovery and development projects and contributed to the registration of more than 45 marketed drug products and the preparation of several hundred IND’s.  He has vast experience in the areas of drug metabolism and disposition, toxicology/pathology, genetic toxicology, pharmacokinetics/toxicokinetics and all aspects of investigative toxicology. He is well grounded in biochemistry, cell biology, molecular biology and pharmacology with the ability to integrate data from the different preclinical disciplines to enable translation to determine the clinical relevance of the findings. He is very familiar with global drug registration requirements and working on global projects.  He has authored more than 80 scientific publications, has lectured in toxicology at the University of Basel for more than 30 years, and is a past President of the European Society of Biochemical Pharmacology and the Swiss Society of Toxicology. He was a member of the PhRMA/IQ Preclinical Leadership (DruSafe) Committee for 16 years, a member of the advisory board of the PSTC Biomarker consortium and a member of the expert working group for revision of the ICH S2 guidance on genotoxicity testing and the PhRMA expert group on genotoxic impurities.  He has a BSc and PhD in Biochemistry from the University of Hull, UK and held Post-Doctoral Fellowships at the University of Basel, Switzerland and Mainz, Germany.

Research Interest

product development , biotechnology , Business management

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