Sinead Miggin
Lecturer, MSc in Immunology & Global Health Coordi
Department of Biology
National University of Maynooth
Ireland
Biography
Dr Sinead Miggin graduated in Toxicology from Athlone Institute of Technology. In 2000, she was awarded a PhD in Biochemistry which was undertaken at the Conway Institute, University College Dublin. She subsequently undertook a Postdoctoral Fellowship in Inflammation research at the Conway Institute (2000-2002) followed by a Senior Postdoctoral Fellowship at the Department of Biochemistry and Immunology, Trinity College Dublin, Ireland (2002-2006). She was appointed Lecturer in Immunology at the National University of Ireland Maynooth in 2006. In 2015, Dr Miggin was awarded a Postgraduate Diploma in Higher Education.
Research Interest
Thromboxane A 2 receptor mediated activation of the mitogen activated protein kinase cascades in human uterine smooth muscle cells.
Publications
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Miggin SM, Kinsella BT. Expression and tissue distribution of the mRNAs encoding the human thromboxane A 2 receptor (TP) α and β isoforms. Biochimica et Biophysica Acta (BBA)-General Subjects. 1998 Nov 27;1425(3):543-59.
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Lawler OA, Miggin SM, Kinsella BT. Protein kinase A-mediated phosphorylation of serine 357 of the mouse prostacyclin receptor regulates its coupling to Gs-, to Gi-, and to Gq-coupled effector signaling. Journal of Biological Chemistry. 2001 Sep 7;276(36):33596-607.
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Miggin SM, O’neill LA. New insights into the regulation of TLR signaling. Journal of leukocyte biology. 2006 Aug 1;80(2):220-6.