Aiden Corvin

Biography

I completed undergraduate medical training at University College Cork in 1993 and Membership of the Royal College of Psychiatrists (UK) in 1998. I was awarded a Wellcome Trust Research Training Fellowship in Mental Health in 2000 to develop my interest in the genetic etiology of psychosis and founded the Psychosis Research Group (www.medicine.tcd.ie/neuropsychiatric-­â€genetics/psychosis/). I was appointed Senior Lecturer in Psychiatry at TCD (now Professor) and Consultant Psychiatrist at St James's Hospital, Dublin in 2006. Since its inception my research group's goal has been to identify and investigate genetic mechanisms of psychosis, to define molecular etiology, and to use this information to serve patients by improving diagnostics and developing new therapeutic approaches. Through the commitment of more than 3,000 Irish participants we have contributed to substantial research breakthroughs in the field. From identifying molecular overlap between schizophrenia, bipolar disorder, and other psychiatric disorders; to going from finding the first identified risk genes, to the recent confirmation of 108 schizophrenia risk loci. We have identified novel, but rare large genetic effects that may be particularly important in understanding the underlying biology involved. We are increasingly interesting in modeling the risk mechanisms involved and looking at the extent of overlap with other neurological disorders (Brainstorm Project). I am a founder member of the International Schizophrenia Consortium, and lead the Wellcome Trust Case Control Consortium 2-schizophrenia study and Brainstorm (with Ben Neale, Broad Institute MIT/Harvard). I am Associated Editor for Genetics for the Schizophrenia Bulletin. I have authored 190 publications in international peer reviewed journals (Nature, Nature Genetics, Human Molecular Genetics, JAMA Psychiatry) and published 8 book chapters. My group's work has been funded by the Wellcome Trust, NIH, EU, Health Research Board, and Science Foundation Ireland. My h-index (Google Scholar, July 2014)is 43

Research Interest

Aetiology of mental illness; Cognitive dysfunction in psychotic disorders; Neurodegenerative diseases including schizophrenia & Alzheimer's disease; Neurogenetics; Psychiatric genetics; Schizophrenia