Charles Dorman
Professor
Microbiology
Trinity College Dublin
Ireland
Biography
Charles J Dorman is a microbial geneticist and has held the Chair of Microbiology at Trinity College Dublin since 1994. In 2017 he was elected to a third 3-year term as head of the School of Genetics and Microbiology. Professor Dorman has been a Science Foundation Ireland Principal Investigator since 2003, is a Founding Member of the European Academy of Microbiology, a Fellow of the American Academy of Microbiology, a Member of the Royal Irish Academy (Ireland's highest academic honour), a Fellow of the Royal Society of Biology and was made a Chartered Biologist by the Institute of Biology in 2009. He is a recipient of the Sir Alexander Fleming Medal of the Society for General Microbiology (SGM) and was formerly a Royal Society Research Fellow and Lecturer in Biochemistry at the Medical Sciences Institute at Dundee University in the United Kingdom. Professor Dorman has served as the Ambassador to Western Europe and Israel of the American Society for Microbiology (ASM) and is a member of the ASM Committee on Global Engagement. He has a keen interest in the development of microbiology internationally, is a visiting professor at the Indian Institute of Science at Bangalore and has delivered around 200 invited lectures at conferences, universities and research institutes around the world over the past twenty-five years. From 2005 to 2010 Professor Dorman was Editor-in-Chief of 'Microbiology' (published by the SGM) and in 2014 was elected chair of the SGM Publishing committee with responsibility for its six scientific journals; in 2015 he launched its latest journal, MGen (Microbial Genomics) a fully-open-access, online journal. He has served on the editorial boards of numerous scientific journals and has been an advisor to several national and international research funding agencies worldwide. In 2006-07 he chaired a review of all microbiological research in the United Kingdom for the Biotechnology and Biological Sciences Research Council (BBSRC). His own research focuses on the global regulation of gene expression in bacteria of medical importance, with an emphasis on the regulatory roles of DNA topology and nucleoid-associated proteins. Professor Dorman is currently a Trustee of the Microbiology Society (London) and a member of its governing council.
Research Interest
Gene regulatory mechanisms in Gram-negative bacteria of medical importance, with an emphasis on the roles of nucleoid-associated proteins and DNA topology in controlling transcription and site-specific recombination. 2. Horizontal transfer of gene regulatory elements and the evolution of gene control networks. 3. The dissection and interpretation of complex gene regulatory circuits using genomics methods. 4. Modulation of gene expression patterns in pathogenic bacteria during infection and intracellular growth.
Publications
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Quinn HJ, Cameron ADS, Dorman CJ, Bacterial regulon evolution: distinct responses and roles for the identical OmpR proteins of Salmonella Typhimurium and Escherichia coli in the acid stress response, PLoS Genetics, 10, (3), 2014, pe1004215
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Paytubi S, Aznar S, Madrid C, Balsalobre C, Dillon S, Dorman CJ, Juarez A, A novel role for antibiotic resistance plasmids in facilitating Salmonella adaptation to nonhost environments, Environmental Microbiology, 16, (4), 2014, p950 - 962
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Coordination of bacterial virulence gene expression (Chapter 17) in, editor(s)Y-W Tang , Molecular Medical Microbiology 2nd Edition , San Diego, Elsevier, 2014, pp315 - 355, [Dorman CJ]
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Dorman, C.J., Agnès fouet - Departing Editor-in-chief, Microbiology (United Kingdom), 161, (6), 2015
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Fitzgerald S, SC Dillon, C Tzu-Chiao, HL Wiencko, K Hokamp, ADS Cameron, CJ Dorman, Re-engineering cellular physiology by rewiring high-level global regulatory genes, Scientific Reports, 5, 2015, p17653
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Dorman, CJ, Integrating small molecule signalling and H-NS antagonism in Vibrio cholerae, a bacterium with two chromosomes, Molecular Microbiology, 97, (4), 2015, p612 - 615,
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Dorman CJ, Function of nucleoid-associated proteins in chromosome structuring and transcriptional regulation, Journal of Molecular Microbiology and Biotechnology, 24, (6), 2015, p316 - 331
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Dorman CJ, Dorman MJ, DNA supercoiling is a fundamental regulatory principle in the control of bacterial gene expression, Biophysical reviews, 8, (suppl 1), 2016, p89 - 100
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Dorman CJ, MM Bogue, The interplay between DNA topology and accessory factors in site-specific recombination in bacteria and their bacteriophages, Science Progress, 99, (4), 2016, p420 - 437
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Dorman CJ, MJ Dorman, DNA supercoiling is a fundamental regulatory principle in the control of bacterial gene expression, Biophysical Reviews, 8, (3), 2016, p209 - 220,
