Clare Kelly
Assistant Professor
sychology
Trinity College Dublin
Ireland
Biography
I received my BA in Psychology from Trinity College Dublin in 2002. Shortly after graduating, I joined the lab of Hugh Garavan, PhD, and began to use functional magnetic resonance imaging (fMRI) to non-invasively assess human brain structure and function. My doctoral research used fMRI to examine cognitive control processes, individual differences, and practice effects in healthy adults, and in 2006 I graduated from Trinity College with a PhD in Cognitive Neuroscience. Upon completion of my PhD, I joined the research group of Drs. F. Xavier Castellanos and Michael P. Milham at the New York University Child Study Center, first as a Postdoctoral Fellow, then as an Associate Research Scientist, and ultimately as an Assistant Professor. Since that time, my research has focused on the development, validation, and application of frontier brain imaging approaches to ascertain the functional and structural architecture of the brain in healthy, developing, and disordered human populations. In January of 2015, I returned to Trinity College to become an Ussher Assistant Professor of Functional Neuroimaging, working at Trinity College Institute of Neuroscience (TCIN), with a joint appointment in the School of Psychology and Department of Psychiatry at the School of Medicine. Here at TCD, my lab continues to forge a research mission aimed at elucidating the neurodevelopmental bases of psychiatric disorders through the application and refinement of frontier functional and structural neuroimaging methods. My research vision is to trace the roots of mental health difficulties in the developing brain, so that we can identify at-risk individuals at the earliest possible point and intervene to divert their developmental trajectory away from illness towards health.
Research Interest
Developing, validating, and applying frontier brain imaging approaches to map typical and atypical development of the brain's functional and structural architectures, so that we can understand where, when, and how development can go awry. - Understanding brain-behaviour relationships - how interindividual differences in brain structure and function produce interindividual differences in behaviour. I am particularly interested in higher order cognitive functions such as working memory and attentional control, as well as in motivational functions related to learning and reward processing. - Identifying and characterising dysfunctional brain organisation and brain dysconnectivity in clinical populations such as attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), mood disorders, and substance use and addiction. - Understanding the impact of early life experience on brain function, behaviour, and long-term mental health outcomes.
Publications
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Shehzad Z, Kelly C, Reiss PT, Cameron Craddock R, Emerson JW, McMahon K, Copland DA, Castellanos FX, Milham MP, A multivariate distance-based analytic framework for connectome-wide association studies., NeuroImage, 93 Pt 1, 2014, p74-94
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Di Martino A, Fair DA, Kelly C, Satterthwaite TD, Castellanos FX, Thomason ME, Craddock RC, Luna B, Leventhal BL, Zuo XN, Milham MP, Unraveling the miswired connectome: a developmental perspective., Neuron, 83, (6), 2014, p1335-53
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Jacobson McEwen SC, Connolly CG, Kelly AM, Kelleher I, O Hanlon E, Clarke M, Blanchard M, McNamara S, Connor D, Sheehan E, Donohoe G, Cannon M, Garavan H, Resting-state connectivity deficits associated with impaired inhibitory control in non-treatment-seeking adolescents with psychotic symptoms., Acta psychiatrica Scandinavica, 129, (2), 2014, p134-42
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Zuo XN, Anderson JS, Bellec P, Birn RM, Biswal BB, Blautzik J, Breitner JC, Buckner RL, Calhoun VD, Castellanos FX, Chen A, Chen B, Chen J, Chen X, Colcombe SJ, Courtney W, Craddock RC, Di Martino A, Dong HM, Fu X, Gong Q, Gorgolewski KJ, Han Y, He Y, He Y, Ho E, Holmes A, Hou XH, Huckins J, Jiang T, Jiang Y, Kelley W, Kelly C, King M, LaConte SM, Lainhart JE, Lei X, Li HJ, Li K, Li K, Lin Q, Liu D, Liu J, Liu X, Liu Y, Lu G, Lu J, Luna B, Luo J, Lurie D, Mao Y, Margulies DS, Mayer AR, Meindl T, Meyerand ME, Nan W, Nielsen JA, O Connor D, Paulsen D, Prabhakaran V, Qi Z, Qiu J, Shao C, Shehzad Z, Tang W, Villringer A, Wang H, Wang K, Wei D, Wei GX, Weng XC, Wu X, Xu T, Yang N, Yang Z, Zang YF, Zhang L, Zhang Q, Zhang Z, Zhang Z, Zhao K, Zhen Z, Zhou Y, Zhu XT, Milham MP, An open science resource for establishing reliability and reproducibility in functional connectomics., Scientific data, 1, 2014, p140049
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Shpaner M, Kelly C, Lieberman G, Perelman H, Davis M, Keefe FJ, Naylor MR, Unlearning chronic pain: A randomized controlled trial to investigate changes in intrinsic brain connectivity following Cognitive Behavioral Therapy., NeuroImage. Clinical, 5, 2014, p365-76
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Vanderwal T, Kelly C, Eilbott J, Mayes LC, Castellanos FX, Inscapes: A movie paradigm to improve compliance in functional magnetic resonance imaging., NeuroImage, 122, 2015, p222-32
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Somandepalli K, Kelly C, Reiss PT, Zuo XN, Craddock RC, Yan CG, Petkova E, Castellanos FX, Milham MP, Di Martino A, Short-term test-retest reliability of resting state fMRI metrics in children with and without attention-deficit/hyperactivity disorder., Developmental cognitive neuroscience, 15, 2015, p83-93
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Alaerts K, Nayar K, Kelly C, Raithel J, Milham MP, Di Martino A, Age-related changes in intrinsic function of the superior temporal sulcus in autism spectrum disorders., Social cognitive and affective neuroscience, 10, (10), 2015, p1413-23
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Chen H, Kelly C, Xavier Castellanos F, Hed Y, Zuo XN, Reiss PT, Quantile rank maps: A new tool for understanding individual brain development., NeuroImage, 2015
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Yoncheva YN, Somandepalli K, Reiss PT, Kelly C, Di Martino A, Lazar M, Zhou J, Milham MP, Castellanos FX, Mode of Anisotropy Reveals Global Diffusion Alterations in Attention-Deficit/Hyperactivity Disorder., Journal of the American Academy of Child and Adolescent Psychiatry, 55, (2), 2016, p137-45
