Daniel J Kelly
Professor
Mechanical & Manufacturing Engineering
Trinity College Dublin
Ireland
Biography
Dr Daniel Kelly is the Professor of Tissue Engineering in Trinity College Dublin and Director of the Trinity Centre for Bioengineering (TCBE). He is also one of the founding Principal Investigators of the Advanced Materials and Bioengineering Research (AMBER) centre based in Trinity College Dublin. Prof Kelly is a current or past recipient of a Science Foundation Ireland President of Ireland Young Researcher Award, a Fulbright Visiting Scholar grant (at the Department of Biomedical Engineering in Columbia University, New York) and three European Research Council awards (Starter grant 2010; Consolidator grant 2015; Proof of Concept grant 2017). His research focuses on developing novel tissue engineering and 3D bioprinting strategies to regenerate damaged and diseased musculoskeletal tissues. To date he has published over 130 articles in peer-reviewed journals.
Research Interest
Arthritis; Bioengineering; Biomaterials; Biomechanics; Biomechanics, Biomedical Engineering; Biomolecules, Bioplastics, Biopolymers; Bioreactors; Cardiovascular System; Computational Biology; Computer-Aided Engineering; Mathematical modelling; Mechanical Engineering; Mechanics; Medical Devices Engineering; Solid Mechanics; Stem Cell; STEM-CELLS; STENTS; Tissue Engineering
Publications
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Sridharan, R., Cameron, A.R., Kelly, D.J., Kearney, C.J., O Brien, F.J., Biomaterial based modulation of macrophage polarization: A review and suggested design principles, Materials Today, 18, (6), 2015, 313-325
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Luo L., Thorpe S.D., Buckley C.T. and Kelly D.J. , The effects of dynamic compression on the development of cartilage grafts engineered using bone marrow and infrapatellar fat pad derived stem cells, Biomedical Materials, 21, (10(5)), 2015, p055011
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Thompson EM, Matsiko A, Farrell E, Kelly DJ, O Brien FJ, Recapitulating endochondral ossification: a promising route to in vivo bone regeneration., Journal of tissue engineering and regenerative medicine, 9, (8), 2015, p889-902
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Mesallati T., Buckley C.T. and Kelly D.J. , Engineering cartilaginous grafts using chondrocyte-laden hydrogels supported by a superficial layer of stem cells, Journal of Tissue Engineering and Regenerative Medicine , 5, (18), 2016, p2353-2362
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O Reilly, A., Kelly, D.J., Unravelling the Role of Mechanical Stimuli in Regulating Cell Fate During Osteochondral Defect Repair, Annals of Biomedical Engineering, 44, (2), 2016, 3446-3459
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Lu, L., Chu, J., Rajalakshmanan, E., Mulhall, K., Kelly, D. J., Engineering tissues that mimic the zonal nature of articular cartilage using decellularized cartilage explants seeded with adult stem cells., ACS Biomaterials Science & Engineering , 2016
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Luo, L., O Reilly, A.R., Thorpe, S.D., Buckley, C.T., Kelly, D.J., Engineering zonal cartilaginous tissue by modulating oxygen levels and mechanical cues through the depth of infrapatellar fat pad stem cell laden hydrogels, Journal of Tissue Engineering and Regenerative Medicine, 2016
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Almeida, H.V., Mulhall, K.J., O Brien, F.J., Kelly, D.J., Stem cells display a donor dependent response to escalating levels of growth factor release from extracellular matrix-derived scaffolds, Journal of Tissue Engineering and Regenerative Medicine, 2016, p1-9-
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Verrier, S., Alini, M., Alsberg, E., Buchman, S.R., Kelly, D., Laschke, M.W., Menger, M.D., Murphy, W.L., Stegemann, J.P., Schütz, M., Miclau, T., Stoddart, M.J., Evans, C., Tissue engineering and regenerative approaches to improving the healing of large bone defects, European Cells and Materials, 32, 2016, p87-110
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Saha, A., Rolfe, R., Carroll, S., Kelly, D.J., Murphy, P., Chondrogenesis of embryonic limb bud cells in micromass culture progresses rapidly to hypertrophy and is modulated by hydrostatic pressure, Cell and Tissue Research, 2016, p1-13
