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Lucy Norris

SENIOR EXP OFFICER
Obstetrics
Trinity College Dublin
Ireland

Biography

Lucy Norris graduated from Trinity College Dublin with an honours degree in Biochemistry. She was awarded a PhD in 1992 from TCD Dept of Obstetrics and Gynaecology based on her work investigating platelet activation in pregnancy, pre-eclampsia and oral contraception. She was PI on several large scale studies investigating the mechanisms of haemostatic activation in hormone users (OC and HRT) collaborating with key figures in the field in Europe and North America and writing two consensus documents in this area. In 2002, she was awarded an MSc in Molecular Medicine from TCD and following this has established a group investigating the molecular effects of hormones on coagulation gene expression funded by the Health Research Board. Lucy's interests also extend to pregnancy where, in collaboration with Prof John Higgins in UCC, she is currently investigating new biomarkers to predict venous thrombosis in pregnancy and also the effects of LMWH on thrombin production in high risk pregnancy groups such as the obese. In collaboration with Dr. Noreen Gleeson and Prof. John O'Leary, her research programme has also extended to gynaecological cancers; the role of coagulation gene expression in the aetiology of ovarian cancer and in prediction of venous thrombosis post gynaecological surgery is currently being investigated (funded by the HRB). She has over 60 peer reviewed publications, many as senior author, including 5 invited reviews. She is a member of the International Society for Thrombosis and Haemostasis and is a member of the editorial board for the journal 'Thrombosis Research'.

Research Interest

Biomedical sciences; Cardiovascular risk assessment and hormone replacement therapy; Clinical research, trials; Coagulation biochemistry and disorders; Cytokines, Nitric Oxide; Foetal, maternal and neonatal physiology; Haemotology; Hormone physiology and biochemistry; Inflammation and coagulation syndromes; Medical Sciences, Research; Menopause; Molecular haematology; Oral contaraceptives and haemostasis; Pre-eclampsia and intrauterine growth retardation; Prevention, treatment of thromboembolic complications in pregnancy; Reproduction, fertility and contraception; Thrombosis and haemostasis; Vascular Biology, Thrombosis

Publications

  • Norris LA, Martin FA, O Toole SA, Saadeh FA, Gleeson N, PO-24 - Determinants of thrombin generation in gynaecological malignancies., 2016

  • Abu Saadeh, F, Langhe R, Galvin DM, O Toole SA, O Donnell DM, Gleeson N, Norris LA, Procoagulant activity in gynaecological cancer patients; the effect of surgery and chemotherapy. , Thrombosis Research, 139, 2016, p135 - 141

  • Petch S, Norris L, O Toole S, Gleeson N, Abu Saadeh F., Peri operative venous thromboembolism prophylaxis in gynaecological cancer patients. A survey of current practice, Thrombosis Research, 145, 2016, p126 - 128

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