Maria Jose Santos-martinez
Assistant Professor
Nanopharmaceutical Drug Discovery
Trinity College Dublin
Ireland
Biography
Asst. Prof. Maria J. Santos-Martinez MD, PhD Assistant Professor (Ussher) School of Pharmacy and Pharmaceutical Sciences and School of Medicine Email: santosmm@tcd.ie Phone: +353-1-896-4281 Location: Panoz Institute, Trinity College, Dublin 2, Ireland. Biological Safety Officer. Course Coordinator for Community Pharmacy.
Research Interest
Maria J. Santos-Martinez is a Spanish medical doctor specialist in Respiratory Medicine. Her research interests are mainly focused on blood platelets - cancer - nanoparticles and their interactions: Application of Quartz Crystal Microbalance with Dissipation (QCM-D) technology to platelets, cancer cells and nanomaterials. Platelet biology and pharmacology. Contribution of platelets to cancer progression (tumor invasion, angiogenesis and blood metastastasis). Nanoparticle-cell and nanoparticle-platelet interactions (Nanotoxicology). Interactions between nanoparticles developed for drug delivery, their targets and the potential barriers that they have to be overcome to exert their action.
Publications
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Santos-Martinez, M.J., Tomaszewski, K., Medina, C., Bazou, D., Gilmer, J.F., Radomski, M.W. , Pharmacological characterization of nanoparticle-induced platelet microaggregation using quartz crystal microbalance with dissipation: comparison with light aggregometry, International Journal of Nanomedicine, 10, 2015, p5107 - 5119
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Umerska A, Paluch KJ, Santos-Martinez MJ, Medina C, Corrigan OI, Tajber L, Chondroitin-based nanoplexes as peptide delivery systems--Investigations into the self-assembly process, solid-state and extended release characteristics., European Journal of Pharmaceutics and Biopharmaceutics, 93, 2015, p242 - 253
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Larkin, C.M., Santos-Martinez, M.-J., Ryan, T., Radomski, M.W., Sepsis-associated thrombocytopenia, Thrombosis Research, 141, 2016, p11-16
