Steven Gray
Assistant Professor
Clinical Medicine
Trinity College Dublin
Ireland
Biography
Steven Gray graduated from Trinity College Dublin in 1992. He joined the laboratory of Tomas J. Ekstrom at the Karolinska Institute in 1996 and received his PhD in 2000 (Thesis Title: The IGF-axis in liver disease: Modulation of expression by histone deacetylase inhibitors). He moved to the Van Andel Research Institute in Michigan, USA where he continued his studies on the therapeutic potential of histone deacetylase inhibitors in the treatment of cancer. He also spent some time as a visting fellow at Harvard Medical School, Boston working on epigenetic therapies for neurodegenerative disease. Returning to Europe Dr Gray spent some time at the German Cancer Research Centre (DKFZ - Heidelberg), and subsequently moved to Copenhagen to work for Novo Nordisk as part of the research team of Prof Pierre De Meyts at the Hagedorn Research Institute working on epigenetic mechanisms underpinning diabetes pathogenesis. Dr Gray is currently a senior clinical scientist at St James's Hospital in the Deprtment of Clinical Oncology at the Thoraacic Oncology Research Group at St. James's Hospital headed by Dr. Sinead Cuffe and Professor Stephen Finn, and holds an adjunct assistant professorship with the Dept of Clinical Medicine (TCD).
Research Interest
CANCER; CANCER BIOPSIES; CANCER CELL-LINE; CANCER CELLS; CANCER CHEMOTHERAPY; CANCER CLASSIFICATION; CANCER DEVELOPMENT; CANCER INVASION; CANCER SUSCEPTIBILITY GENE; CANCER-CELLS; CANCERS; CARCINOMA; CARCINOMA CELL-LINES; CARCINOMA, RENAL CELL; CARCINOMA-CELLS; CARCINOMAS; CELL; Cellular Biology; CHROMATIN; Cloning of Cells; Cytogenetics; DNA MARKERS; DNA METHYLATION; EPIDERMAL GROWTH FACTOR RECEPTOR; Epigenetics; GENE EXPRESSION; GENE EXPRESSION ANALYSIS; GENE-EXPRESSION; Genetics; GENOME; Genomes, Genomics; GENOMICS; GROWTH FACTOR RECEPTOR; Histology; Histology, Cytochemistry, Histochemistry; HISTONE; HISTONE DEACETYLASE COMPLEX; INSULIN; INSULIN RESISTANCE; INSULIN-LIKE GROWTH FACTOR I AND II; Life Sciences; METASTASIS; Molecular Biology; Molecular Genetics; Systematic Biology; Tissue Culture; Transcription
Publications
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Cregan S, McDonagh L, Gao Y, Barr MP, O Byrne KJ, Finn SP, Cuffe S, Gray SG, KAT5 (Tip60) is a potential therapeutic target in malignant pleural mesothelioma., International journal of oncology, 48, (3), 2016, p1290-6
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Joerger, M., Finn, S.P., Cuffe, S., Byrne, A.T., Gray, S.G., The IL-17-Th1/Th17 pathway: an attractive target for lung cancer therapy?, Expert Opinion on Therapeutic Targets, 20, (11), 2016, 1339-1356
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MacDonagh L, Gray SG, Breen E, Cuffe S, Finn SP, O'Byrne KJ, Barr MP, Lung cancer stem cells: The root of resistance., Cancer letters, 372, (2), 2016, p147-56
