David Gibson

Biography

After his Biochemistry degree, Dr David Gibson worked at Randox Laboratories Ltd, where he was responsible for designing and commercialising novel biochip array diagnostic tests. He was awarded a PhD in 2001 from the Centre for Cancer Research and Cell Biology, Queen’s University Belfast (QUB), for research which exposed the role of cysteine proteinases in brain tumour invasion. During a Wellcome Trust Fellowship Dr Gibson investigated the role of inflammation in a hypoxia driven model of diabetic retinopathy at the Centre of Vision and Vascular Science, QUB.

Research Interest

Since 2003 Dr Gibson focused his research efforts on the discovery and validation of protein biomarkers which could improve the management of arthritis patients. He employs novel mass spectrometry based methods to robustly identify and quantify disease associated proteins in blood. He is also interested in the application of protein array technologies for autoantibody screening and flow cytometry in measuring B- and T-cell activation. He has established research programmes in three key areas: 1. Mechanisms and biomarkers of resistance to biologic therapies. 2. Mechanisms and biomarkers of response to disease modifying anti-rheumatic drugs. 3. Alternate blood sampling methods to support home based monitoring of arthritis.