School of Biomedical Sciences
Dr Thompson obtained his PhD in Biochemistry and Molecular Biology from Medical College of Ohio in 1993 after which he joined the laboratory of Prof Mark Haussler (University of Arizona) where he first developed an interest in vitamin D and retinoid biology. From 2002-2003, he worked at LION Bioscience AG (Heidelberg, Germany) where he continued to explore nuclear receptor mechanistic functionality before returning to academia at Ulster. As a Senior Lecturer at Ulster, Dr Thompson is interested in how the vitamin D and retinoid pathways regulate the expression of metabolic gene products and their relevance to endobiotic/drug bioavailability in addition to such diseases as prostate cancer and melanoma.
Dr Thompson’s lab is interested in deciphering how vitamin D and retinoid derived compounds govern the expression of transcriptional networks important for metabolic function and maintenance of healthy aging and how such effects are mediated through nuclear receptors such as vitamin D receptor (VDR) and retinoid X receptor (RXR)