Global

Neurology Experts

Antonella Bobba

Senior Researcher
Department ob Biomembranes and Bioenergetics
Institute for Biomembranes and Bioenergetics-CNR
Italy

Biography

"Education and training 1982: Degree in Biological Sciences ""cum laude"" at University of Bari 1984: Researcher at the Centro di Studio sui Mitocondri e Metabolismo Energetico -CNR 2001 Senior Researcher at the Institute of Biomembrane and Bioenergetics (IBBE) Stages 1987 Fellowship at the Institut fuer Physiologische Chemie, Physikalische Biochemie und Zellbiologie der Ludwig-Maximilans-Universitat Munchen, Germany. Professional experience 1984-1993 Member of the Board of Examiners in Biological Chemistry 1990 Member of the Scientific and Organizing Secretariat in the Workshop ""Antigenic Properties of Myelin and the Role of Myelin in Pathology"", Naples 22-23 October 1990 2002-2009 Member of the Institute Committee at IBBE-CNR 2003-to present “Referente Servizi Telematici Interni” at IBBE-CNR 2003-to present “Referente Web” at IBBE-CNR 2010-to present Head of Section (Commessa) “Interrelazione nucleo/ citoplasma/ mitocondri nell'omeostasi cellulare” at IBBE "

Research Interest

"1) characterization of the molecular mechanisms of neurodegeneration. Deciphering the early events of the apoptotic cell death program in neuronal cell cultures 2) Studies concerning the molecular analysis of genetic disease characterized by an high incidence in the Mediterranean area (21-OH deficiency, Wilson Disease, Cystic Fibrosis). 3) Purification and characterization of membrane proteins in non-denaturing conditions. Purification of proteins in native, lipid-bound forms from myelin membrane. Studies on structure and function of myelin proteins and on the interaction of myelin proteins with different ligands and model membranes. 4) Studies on the physiopathological role of myelin proteins in vivo. Interaction of purified native myelin proteins with immunocompetent cells. "

Publications

  • Bobba A, Atlante A, Petragallo P and Marra E. Different sources of reactive oxygen species contribute to low potassium-induced apoptosis in cerebellar granule cells (2008) Int J Mol Med. 21, 737-745.

  • Atlante A, Bobba A, Paventi G, Pizzuto R, Passarella S. Genistein and daidzein prevent low potassium-dependent apoptosis of cerebellar granule cells. (2010) Biochem Pharmacol. 79, 758–767

  • Bobba A, Petragallo VP, Marra E, and Atlante A, “Alzheimer's Proteins, Oxidative Stress, and Mitochondrial Dysfunction Interplay in a Neuronal Model of Alzheimer's Disease,” (2010) International Journal of Alzheimer's Disease, vol. 2010, Article ID 621870, 11 pages,. doi:10.4061/2010/621870

Global Experts from Italy

Global Experts in Subject

Share This Profile
Recent Expert Updates
  • Matthew L Stone
    Matthew L Stone
    pediatrics
    University of Virginia Health System; Charlottesville, VA
    United States of America
  • Dr.   Matthew
    Dr. Matthew
    pediatrics
    University of Virginia Health System; Charlottesville, VA
    United States of America
  • Dr.  L Stone Matthew
    Dr. L Stone Matthew
    pediatrics
    University of Virginia Health System; Charlottesville, VA
    United States of America
  • Dr.  L Stone
    Dr. L Stone
    pediatrics
    University of Virginia Health System; Charlottesville, VA
    United States of America
  • Dr. Matthew L Stone
    Dr. Matthew L Stone
    pediatrics
    University of Virginia Health System; Charlottesville, VA
    United States of America
  • Dr.  R Sameh
    Dr. R Sameh
    pediatrics
    King Abdul Aziz University
    United Arab Emirates
  • Dr.   R Ismail,
    Dr. R Ismail,
    pediatrics
    King Abdul Aziz University
    United Arab Emirates
  • Sameh R Ismail,
    Sameh R Ismail,
    pediatrics
    King Abdul Aziz University
    United Arab Emirates
  • Dr.   Sameh R Ismail,
    Dr. Sameh R Ismail,
    pediatrics
    King Abdul Aziz University
    United Arab Emirates
  • Dr.   William
    Dr. William
    pediatrics
    Maimonides Medical Center
    United States of America