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Rosa Lippolis

Technologist
Department ob Biomembranes and Bioenergetics
Institute for Biomembranes and Bioenergetics-CNR
Italy

Biography

"Education and training 1979: Degree in Biological Sciences at University of Bari 1982: Research grant at the Center for Study of Mitochondria and Energy Metabolism (CSMME) -CNR 1990: Technologist at the Center for Study of Mitochondria and Energy Metabolism (CSMME), later became institute Biomenbrane and Bioenergetics. (IBBE) - CNR, Bari. Professional experience 2004. Head of the IBBE Proteomics section. 2007-2010. Participate in the project MUR-FAR ""Laboratorio pubblico-privato per lo sviluppo di processi e prodotti innovative nel campo dei farmaci antinfettivi” (LIFA). 2004. Be part of the commessa SV-P14.005, ""Membrane bioenergetics systems: functional mechanism and pathophysiology"" Macrolinea 015.001. 2011. Reporting Officer the CNR laboratory N.1.34 at the Department of Medical Biochemistry, Medical Biology and Medical Physics (DIBIFIM) of the University of Bari. 2013. Reporting Officer and DPI Head of the Proteomics Laboratory of the Department of Basic Medical Sciences Neuroscience and Sense Organs, of the University of Bari. 2013. Reviewer for the scientific journal: Mitochondrion."

Research Interest

"1. Study specific protein expression profile of microorganism of clinical and pharmaceutical interest by advanced proteomics. 2. Structural and functional characterization of molecules with potential biological activity. 3. Study of the role of trans retinoic acid (ATRA) on the biogenesis and activity of complex I of the mitochondrial respiratory chain, in human keratinocytes. 4. Proteomic characterization of the nasal mucosa cells of patients affected by various forms of rhinitis. 5. Study of the expression profile of fibroblasts from patients with Parkinson's Disease for identification of proteins associated with the pathologic state. 6. Study of cellular metabolism in the processes of proliferation, differentiation and cell death, with particular reference to mitochondrial functions.

Publications

  • Lippolis R, Siciliano RA, Pacelli C, Ferretta A, Mazzeo MF, Scacco S, Papa F, Gaballo A, Dell'Aquila C, De Mari M, Papa S, Cocco T. Altered protein expression pattern in skin fibroblasts from parkin-mutant early-onset Parkinson's disease patients. Biochim Biophys Acta. 2015 Sep;1852(9):1960-70.

  • Ballini A. Cantore S, Farronato D, Cirulli N, Inchingolo F, Papa F, Malcangi G, Inchingolo AD, Dipalma G, Sardaro N, Lippolis R, Santacroce L, Coscia MF, Pettini F, De Vito D, Scacco S. Periodontal disease and bone pathogenesis: the crosstalk between cytokines and porphyromonas gingivalis. J Biol Regul Homeost Agents. 2015 Apr-Jun;29(2):273-81.

  • Mazzeo MF, Lippolis R, Sorrentino A, Liberti S, Fragnito F, Siciliano RA. Lactobacillus acidophilus - rutin interplay investigated by proteomics. 2015, PLOS ONE in press.

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