Sergio Giannattasio

Biography

"Positions 2001-at present CNR senior scientist at Istituto di Biomembrane e Bioenergetica (IBBE, formerly Centro di Studio sui Mitocondri e Metabolismo Energetico, CSMME) 1998-2001 CNR research assistant at CSMME 1990-1998 CNR contract research assistant at CSMME 1984-1989 CNR contract research assistant at CSMME 1983 Young research fellow at the Istituto di Chimica Biologica of Bari University October 2010 Visiting senior scientist at the Department of Biological Sciences, The University of New Orleans, New Orleans, LA, USA August 2008 Visiting senior scientist at the Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, NY, USA May 2005 Visiting senior scientist at the Departemento de Biologia, Universidade do Minho, Braga, Portogallo. August 2005 Visiting senior scientist at the Department of Molecular Biology, University of Texas Southwestern Medical Center at Dallas, Texas, USA. 2003-2004 Visiting senior scientist on leave at the Department of Molecular Biology, University of Texas Southwestern Medical Center at Dallas, Texas, USA March-May 1986, May-July 1989, June-July 1996 Guest scientist at the Biochemisches Institut der Universität Zürich, Zurigo, Svizzera December 1995 Visiting research fellow at the Istituto di Clinica Pediatrica of Turin University. February 1991 and March 1993 Visiting research fellow at the Dipartimento di Scienze Biomediche e Oncologia Umana, Turin University He is member of CNR panel of Project Managing Experts. Since June 2009 he is member of the Scientific Board of CNR - IBBE. Project leader 2011-2012 Research Unit CNR–IBBE, APQ Regione Puglia, Networks of Public Research Laboratories, Project “BioNet – PTP, Biodiversity for the exploitation and safety of Apulian typical food productions” 2005-2008 Interreg III/A programme, Project “Trasferimento Innovazione ed Organizzazione nella Ricerca, nella Cultura, nell’Ambiente e nella Sanità” (TIORCAS) 2 (https://serviziweb.unimol.it/pls/unimol/consultazione.mostra_pagina?id_pagina=3075) Regione Molise-Montenegro, Activity “Prevenzione di Malattie Genetiche Ereditarie”; 1999-2002 FP 4 European Commission Project INCO-Copernicus “Molecular genetic testing in phenylketonuria: a model to assess the quality control system for monogenic disease” (MOLGENT, www.geneticahumana.lt/molgent.htm); 1999 CNR Bilateral Project between CSMME and Institute for Medical Radiobiology Zurich University – PSI, Villigen (CH) ""Mitochondrial biogenesis""; 1997-1998 CNR Bilateral Project between CSMME and Human Genetics Center, Vilnius University, Vilnius (Lithuania) “Genetic homogeneity and heterogeneity in the molecular basis of phenylketonuria”; 1993-1999 CNR CSMME research activity # 07 “Nucleus-cytoplasm-mitochondria cross-talk"". Research activity 1983 Active metabolite transport accross the inner mitochondrial membrane. 1984-1998 Mitochondrial biogenesis; nuclear-encoded mitochondrial protein transport; structure determinants of mitochondrial aspartate aminotransferase intracellular localization; aspartate aminotransferase structure-function relations; protein engineering of B6-dependent protein catalysts. 1990-2008 Studies on the molecular basis of inherited diseases (phenylketonuria, 21-hydroxylase deficiency, cystic fibrosis, Wilson disease, primary cardiomiopathies) 1998-at present Programmed cell death in yeast Saccharomyces cerevisiae; mitochondria role in programmed cell death; nucleus-mitochondria cross-talk in Saccharomyces cerevisiae; rat cerebellar granule cell apoptosis. His reaserch activity is documented by: • 60 articles on international peer-reviewed journals; • 17 articles on books and non-JCR journals; • 10 articles on national non-JCR journals • 110 congress proceedings. He was nvited speaker in national and international scientifc meetings and held seminars in several scientific institutions in Italy and abroad. He organized theoretical/practical courses on protein engineering, molecular biology techniques, molecular genetics in clinical practice and cooperated in organization of scientific meetings. Ad-hoc peer-reviewer for the following international scientific journals: Applied Microbiology and Biotechnology Apoptosis Biochimica Biophysica Acta – Molecular Cell Research Brain Research (Main section) Cell Biology International FEBS Letters FEMS Yeast Research Frontiers in Oncology Human Mutation Journal of Pharmaceutical and Biomedical Analysis Microbiology 3 Molecular Genetics and Metabolism Plant cell and Environment Plos ONE Dr. Giannattasio is a member of the Editorial board of: - Research in Cell Biology (Scientific and Academic Publishing) - Microbial cell (Shared Science Publishers OG) And Guest Editor of the Special Issue “Yeast Stress, Aging, and Death” in Oxidative Medicine and Cellullar Longevity. Project reviewer 2012-today Membro del Research Reviewer Board for Research Programmes and Products del MIUR. 2012-today Member of “Albo degli Esperti FAR” del MIUR (D.D. 30/Ric./2012); 2012 Project reviewer per la Research Foundation - Flanders (Fonds Wetenschappelijk Onderzoek - Vlaanderen, FWO, Belgio). 2009 Project reviewer per la National Science Foundation (NSF) (proposal No.0950363, PIN: 081904). Teaching activity Contract professor at University of Molise (Campobasso and Termoli) and University of Calabria (Cosenza) where he held courses on Biochemistry, Applied Biochemistry, Genetic Engineering, Recombinant DNA Technology. He is member of the teaching staff of PhD school “Applied Biochemisrty and Chemistry”, University of Molise. He tutored PhD students and experimental thesis students in undergraduate Biological Sciences School, Faculty of Sciences, University of Bari. Congress organization 2013-2016 Co-Chair Meeting ""Cell Stress: Survival and Apoptosis"" of the “Associazione di Biologia Cellulare e del Differenziamento” (ABCD). 2013 Chairman of the Parallel Session “Cell Stress: Survival and Apoptosis” in the National ABCD Congress 2013, Ravenna. 2013-14 Scientific Advisory board of the 10th International Meeting on Yeast Apoptosis (IMYAX), 14-18 maggio 2014, Gothenburg, Sweden. 2012 Congress chair of 9th International Meeting on Yeast Apoptosis, 16-20 settembre 2012, Rome, Italy. 2000 5th Baltic Congress of Laboratory Medicine, Session 3. Molecular genetic testing and quality assessment del, Vilnius (Lithuania). 1996 Scientific secretariat of the Congress ""Basi Molecolari in Patologia Umana: Dai geni, al meccanismo, alla terapia"", Bari, December 1996 1994 Scientific secretariat of the Congress ""Recenti progressi sulle basi molecolari in patologia umana"", Bari, November 1994. Awards 2002-03 Research supervisor of the project “Characterization of the Molecular Basis of Phenylketonuria in Italy. Identification of Phenylalanine hydroxylase gene Exon 12 R408W mutation”, carried out by three Bari Liceo Classico “Socrate” students, winner of 2002 edition of FAST/EU “I Giovani e le Scienze” award, and exhibited at the 2003 Intel - International Science & Engineering Fair, Cleveland, Ohio (USA). 4 2001 SIBioC-BIO-RAD Prize for studies on “Molecular diagnosis of phenylketonuria: a model to implement a quality control system for monogenic disease”. 2000 SIBioC 2000 Prize for studies on “A survey on molecular biology in clinical laboratoratories in Apulia Region” 1997 ""Fondazione Gaetano Quagliariello"" Award for his studies on the molecular basis of inherited disease 1994 SIBioC (Italian Society of Clinical Biochemistry and Molecular Biology) '94 Prize for research “Mutation detection by RNA single strand conformation polymorphism (rSSCP)” 1987 Classed second for the S.I.B. (Italian Society for Biochemistry and Molecular Biology) Medal. Dr. Giannattasio is a member of the following scientific societies: Italian Society of Biochemistry and Molecular Biology; Italian Society of Biophysics and Molecular Biology; European Cell Death Organization Italian Environmental Mutagen Society "

Research Interest

"Programmed cell death in yeast Saccharomyces cerevisiae; mitochondria role in programmed cell death; nucleus-mitochondria cross-talk in Saccharomyces cerevisiae; rat cerebellar granule cell apoptosis. His reaserch activity is documented by: • 60 articles on international peer-reviewed journals; • 17 articles on books and non-JCR journals; • 10 articles on national non-J"