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Bernardini Japan Battista


BIOTECHNOLOGY DEPARTMENT AND LIFE SCIENCE (DBSV)
Insubria University
Italy

Biography

After graduating, he was Postdoctoral Research Associate at the Department of Physiology Of the University of Rochester, N.Y. Until 1983 where he studied intercellular junctions (gap junctions). At the Department of Biology at the University of Milan he was involved in the biology of the Gametes using as a model the Xenopus laevis anus. Of the sperm have been studied Ultrastructure, motility and role the last stages of spermogenesis. Fertilization has been studied Correlating fluorescence and electron microscopy techniques to electrophysiology techniques. For These researches, presented at various Gordon Conferences, collaborated with Marie Paule Cosson of the Villefranche sM CNRS and Jerry Hedrick of the University of California at Davis where it was Associate in the Experimental Station in 1987. He used Xenopus embryos also for To develop a biological test for the evaluation of teratogenic risk. In this regard, in 2000, Has been invited to become a Expert Panel "to assess the current validation status of FETAX" Department of Health and Human Services. He has recently studied gene modifications During the evolution of vertebrates, changes in gene expression induced by metals and by Nanoparticles to obtain exposure biomarkers (in collaboration with ECVAM of the Joint Research Center of Ispra), and applied functional genomics to animal biotechnology.

Research Interest

Biotechnology and Molecular Sciences

Publications

  • Bernardini G, Benigni G, Antonangeli F, Ponzetta A, Santoni A (2014) Multiple levels of chemokine receptor regulation in the control of mouse natural killer cell development. Frontiers in Immunology 5: 44

  • Coccini T, Gornati R, Rossi F, Signoretto E, Vanetti I, Bernardini G, Manzo L (2014) Gene Expression Changes in Rat Liver and Testes after Lung Instillation of a Low Dose of Silver Nanoparticles. J Nanomed Nanotechnol 5:227

  • Palombella S, Pirrone C, Cherubino M, Valdatta L, Bernardini G (2017)Identification of reference genes for qPCR analysis during hASC long culture maintenance https://doi.org/10.1371/journal.pone.0170918

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