Sisti Massimo
Contract professor
SCIENCES AND HIGH TECHNOLOGY DEPARTMENT
Insubria University
Italy
Biography
Sisti Massimo, born in Milan on March 24, 1949, holds a Bachelor's Degree in Chemistry (Organic-Biological Address) at the University of Milan in November 1973. In 1973/74, 1975/76, 1976/77, 1977/78 was Organic Chemist for Pharmacology and Sciences Faculty, FF, NN of the University of Milan. On July 15, 1983 Massimo Sisti took up service as a University Researcher of the Discipline Group 84 at the Organic Chemistry Laboratory at the University of Milan, having been the winner of the free competition at the 1st place of a University Researcher bandit with DR 15867 of 29.03.1982 OJ No.121 of 5.05.1982. On July 15, 1986 he received the confirmation as a University Researcher. From 01.01.1985 to 31.10.1998 he was a member of the Department of Organic and Industrial Chemistry at the University of Milan, where he joined the Organic Chemistry Laboratories on the same date with other institutes. On 1.11.1998 Massimo Sisti took up his duties as Professor of the 2nd Organic Chemistry Band (C05X-Organic Chemistry, present CHIM06 Organic Chemistry) at the Faculty of Science MM., FF., NN, headquartered in Como, University of the Inzubria Studies, being the winner of the Contest for University Professorships of the 2nd Band with DD.MM. 22.12.1995 and 29.02.1996-Sector C05X Organic Chemistry. On 31.10.2001 he received the confirmation as Professor of the 2nd Class. He is currently part of the Department of Chemical and Environmental Sciences of the ' The field of scientific interest of Massimo Sisti includes structural, synthetic and spectroscopic research of natural organic substances; new synthetic methodologies in Organic Chemistry; synthesis of new polydaded binders and their paramagnetic metal ion complexes as contrast media for Nuclear Magnetic Resonance in vivo. He is the author of 77 original scientific journals in international journals, 4 patents, 38 communications to Congress, 1 editorial publication. Massimo Sisti has performed an intense teaching activity in organic chemistry courses, both theoretical and experimental.
Research Interest
Organic Reaction Research and Synthesis Methods Investigations on polydaded binders and their complexes with paramagnetic ions such as potential contrast media for Magnetic Resonance Imaging (MRI)
Publications
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S. Aime, M. Botta, E. Garino, S. Geninatti-Crich, G. Giovenzana et al. Non-covalent conjugates between cationic polyamino acids and Gd (III) chelates: a route for seeking accumulation of MRI-contrast agents at tumor targeting sites. Chem. Eur. J, 6, 2609-2617 (2000)
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S. Aime, E. Gianolio, E: Soil, GB Giovenzana, R. Pagliarin et al. Ternary Gd (III) -HSA addicts: evidence for the replacement of internal-spherical water molecules by coordinating groups of the protein.Implications for the design of Contrast Agents for MRI J. Biol. Inorg. Chem., 5, 488-497 (2000)
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S. Aime, M. Botta, L. Frullano, S. Geninatti Crich et al. [GdPCP (H2O)] - a paramagnetic contrast agent designed for improved applications in magnetic resonance imaging. J. Med. Chem., 43, 4017-4024 (2000)