Antonello Mallamaci

Biography

Born in Naples in 1961, Antonello Mallamaci got his Diploma in Pianoforte at the Conservatorio of Naples in 1985 and his Degree in Biological Sciences at the University of Naples in 1990. He worked with Dado Boncinelli (IIGB-CNR, Naples, 1989-1991, and DIBIT-HSR, Milan, 1992-2001) and had stages in the labs of Robb Krumlauf (NIMR-MRC, Mill Hill, UK, 1993), Wolfgang Wurst (GSF, Munich, Germany, 1997) and John Parnavelas (UCL, London, 1999). In 2002, he established the Unit of Cerebral Cortex Development, at the DIBIT-HSR in Milan. In 2006, he moved to SISSA as Associate Professor in Molecular Biology, starting the new Laboratory of Cerebral Cortex Development. In the past, Antonello Mallamaci contributed to reconstruction of molecular mechanisms controlling early cortical specification of the dorsal telencephalon, regionalisation of the cortico-cerebral field and appropriate sizing of distinctive areas arising from it, paying special attention to a small set of evolutionarily conserved transcription factors genes and non-coding RNAs implicated in these processes. More recently, he moved to molecular control of cortico-cerebral astrogenesis and neuronal morphogenesis, and developed innovative methods for RNA-therapy of neurodevelopmental haploinsufficiencies.

Research Interest

Modelling etiopathogenesis of the Foxg1-linked variant of West syndrome, Genetic control of cortico-cerebral astrogenesis