Cecilia Garofalo
Doctor
Contract Senior researcher
Orthopaedic Rizzoli Institute
Italy
Biography
From June 2008: Research associate, at the Laboratory of Experimental Oncology, Development of Bimolecular Therapies, Rizzoli Orthopaedic Institute. Project: Efficacy of and resistance to anti-IGF1R targeted therapy in Ewing’s sarcoma. Role of Insulin Receptor in sarcomas. December 2006 - May 2008: Post Doc at the “Health Center” of the University of Calabria. Project: Nuclear Interaction between androgen receptor and IRS1 in breast cancer. December 2003 - November 2006: PhD fellow at the “Health Center” of the University of Calabria. Project: Biomolecular mechanisms of cross-talk between nuclear steroid hormones and IGF1 system. April 2001 - July 2004: Research associate at the Immunology and microbiology department, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA (USA). Project: Role of leptin in breast cancer. July 1998 - November 2003: Residency fellow at the “Health Center” of the University of Calabria. Project: Role of IGF1 system in breast cancer: interaction between IRS1 and estrogen receptor. September 1997 - April 1998: Intern student at the Faculty of Pharmacy, University of Paris Sud Paris (France). Project: Pharmacological activities of Anacardium occidentalis.
Research Interest
General Pathology and Genetic Pathology class, Faculty of Pharmacy,
Publications
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Garofalo C, Sisci D, Surmacz E. Leptin interferes with the effects of the antiestrogen ICI 182,780 in MCF-7 breast cancer cells. Clinical Cancer Research. 2004 Oct 1;10(19):6466-75.
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Garofalo C, Koda M, Cascio S, Sulkowska M, Kanczuga-Koda L, Golaszewska J, Russo A, Sulkowski S, Surmacz E. Increased expression of leptin and the leptin receptor as a marker of breast cancer progression: possible role of obesity-related stimuli. Clinical Cancer Research. 2006 Mar 1;12(5):1447-53.
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Garofalo C, Surmacz E. Leptin and cancer. Journal of cellular physiology. 2006 Apr 1;207(1):12-22.