Cosimelli Barbara

Biography

July 1981: Classical Maturity Diploma at Liceo-Ginnasio "Dante" in Florence. April 1989: Laurea in Chimica at the University of Florence. July 1989-July 1990: Study bag by EniChem Elastomers for the study of catalytic systems by resonance spectroscopy. AA 1990-1991 Admission to the Doctoral Program in Chemistry (VI Cycle), at the University of Florence. July, 1994: Achievement of the title of Doctor of Research in Chemistry. April 1996: Graduation as an Indefinite Researcher (Group C05X - Organic Chemistry) at the Faculty of Pharmacy of the University of Bologna. April 1999: Confirmation at the end of the next three years. November 2002: Session as a Certified Researcher (SSD CHIM / 06 - Organic Chemistry) at the Faculty of Pharmacy of the University of "Federico II" in Naples through the transfer procedure. December 2003: Attendance as associate professor (SSD CHIM / 08 - Pharmaceutical Chemistry) at the same Faculty.

Research Interest

Cosimelli's scientific activity has always been centered on heterogeneous systems: their design, synthesis, reactivity and structural determination through the use of spectroscopic techniques (NMR and mass); This kind of interest has also been coupled with the search for molecules of pharmaceutical interest. This activity has come to fruition in more than 80 publications on international high impact factors, 1 patent and numerous communications to national and international congresses. The main research lines that can be identified, relative to the period from 2002 to present: i) Synthesis, reactivity, activity-activity-relationship study of active molecules on the central receptor of benzodiazepines; (ii) synthesis, reactivity, structural-activity relationship of translocation protein ligand (TSPO) at mitochondrial level; iii) synthesis, reactivity, study of structure-activity relationship of antagonists and agonists for various adenosine receptors; iv) synthesis, reactivity, multinuclear magnetic resonance study and activity-activity relationship of active molecules on the cardiovascular system.