Greco Giovanni

Biography

Giovanni Greco graduated in Pharmacy in 1986 at the Faculty of Pharmacy of the University of Naples "Federico II" and at the same Faculty in 1991, PhD in Pharmaceutical Sciences. He is employed at the Faculty of Pharmacy - Department of Pharmaceutical and Toxicology Chemistry as a professor of SSD CHIM / 08 (Pharmacy Chemistry): from 1992 to 1998 as a researcher, from 1998 to 2002 as Associate Professor, since 2002 as an extraordinary professor, Since 2005 he has been an ordinary professor. Since 2003 he has been teaching Pharmaceutical and Toxicological Chemistry I for Pharmacy CDD. From 2005 to 2010 he was a member of the Scientific Commission of the Pole of Life Sciences and Technologies, and the Spin Off Technical Commission. Since 2004 he has been a member of the science commission of the University's Quality Center. He was the local head of a research unit involved in major national projects (PRINs) carried out in 2001, 2003, 2005 and 2007, focusing on the study of neurotransmitter receptors. From 2007 to 2012 he has been a member of the Board of Directors of the Division of Pharmaceutical Chemistry (since 2010 as vice-president). His research focuses on the design and synthesis of pharmacologically active molecules. This activity has been realized in over 95 works, including articles and monographs, published in international magazines with a high impact factor. He is the author of some teaching manuals in the field of pharmaceutical chemistry. Most of the research carried out by Prof. Greco was devoted to the following fields: i) computational chemistry and quantitative structure-activity relationships on biologically active compounds; ii) design and synthesis of ligands of the central receptor of benzodiazepines; iii) design and synthesis of translocation protein ligand (TSPO) at mitochondrial level; iv) design and synthesis of reverse transcriptase inhibitors of HIV and HIV integrin as potential anti-AIDS agents v) design and synthesis of selective antagonists and agonists for the various adenosine receptors.

Research Interest

The research activity of Prof. Greco has mainly focused on the design and synthesis of pharmacologically active molecules. This activity has been realized in over 95 works, including articles and monographs, published in international magazines with a high impact factor. Most of the research topics cover the following topics: i) computational chemistry and quantitative structure-activity relationships on biologically active compounds; ii) design and synthesis of ligands of the central receptor of benzodiazepines; iii) design and synthesis of translocation protein ligand (TSPO) at mitochondrial level; iv) design and synthesis of reverse transcriptase inhibitors of HIV and HIV integrin as potential anti-AIDS agents; v) design and synthesis of selective antagonists and agonists for the various adenosine receptors.