Imperatore Concetta

Biography

Dr. Concetta Imperatore has a degree in Pharmaceutical Chemistry and Technology at the Faculty of Pharmacy of the University of Naples "Federico II" on October 26, 1999. At the same University, Dr. Concetta Imperatore has concluded a contract of scientific collaboration (May 2000 - November 2000), with reference to the research program "Biotoxins present in Campus Region's molluscs: chemical analysis, toxicological aspects and monitoring" funded by Campania Region funds. In 2003 he received the title of PhD in "Medicine Science" by discussing a thesis titled "Bioactive Glycolipids from Marine Organisms: Isolation,. He subsequently became the winner of a collaborative grant under the 2000-2006 Regional Operational Program Measure 3-13 "Improving Human Resources in Research and Technological Development". On March 1, 2006 he served as a researcher at the Faculty of Pharmacy of the University of "Federico II" of Naples, Department of Natural Resources Chemistry.

Research Interest

The research activity of Dr. Emperor has been directed to the systematic study of various Poriferi species, which has led to the isolation and structural determination of a hundred metabolites, some already known, others never described in the literature. In particular, the study was aimed at the isolation and structural determination of both Mediterranean and Caribbean sea-buckthorn and glycolipid glycolipids. At the same time it is concerned with the synthesis of glycolipids, structural analogues of those isolated from marine sources, with immunomodulatory activity, for carrying out study-activity studies. Synthesis has led to the development of new synthetic methods in the field of carbohydrate chemistry. Moreover, starting from the results obtained from ' chemical research of the Caribbean sponge Plakortis simplex a new line of research alongside that time in the study of the porphyry. The subject of this research is the in-depth study of the biosynthesis of metabolites found in sponges, using the means of molecular biology. This study is carried out at various levels: first, it determines the biosynthetic origin of the sponges-derived metabolites, which in many cases are actually produced by sponge-fed bacterial bacteria; then the genes responsible for the metabolism biosynthesis are identified; Finally, the genes are cloned and expressed in heterologous hosts, so as to ensure potentially unlimited production of the metabolites. At present, the bacterial origin of the most abundant sponge metabolite has been established The subject of this research is the in-depth study of the biosynthesis of metabolites found in sponges, using the means of molecular biology. This study is carried out at various levels: first, it determines the biosynthetic origin of the sponges-derived metabolites, which in many cases are actually produced by sponge-fed bacterial bacteria; then the genes responsible for the metabolism biosynthesis are identified; Finally, the genes are cloned and expressed in heterologous hosts, so as to ensure potentially unlimited production of the metabolites. At present, the bacterial origin of the most abundant sponge metabolite has been established The subject of this research is the in-depth study of the biosynthesis of metabolites found in sponges, using the means of molecular biology. This study is carried out at various levels: first, it determines the biosynthetic origin of the sponges-derived metabolites, which in many cases are actually produced by sponge-fed bacterial bacteria; then the genes responsible for the metabolism biosynthesis are identified; Finally, the genes are cloned and expressed in heterologous hosts, so as to ensure potentially unlimited production of the metabolites. At present, the bacterial origin of the most abundant sponge metabolite has been established first of all, the biosynthetic origin of sponges-derived metabolites is determined, which in many cases are actually produced by sponge-like bacteria; then the genes responsible for the metabolism biosynthesis are identified; Finally, the genes are cloned and expressed in heterologous hosts, so as to ensure potentially unlimited production of the metabolites. At present, the bacterial origin of the most abundant sponge metabolite has been established first of all, the biosynthetic origin of sponges-derived metabolites is determined, which in many cases are actually produced by sponge-like bacteria; then the genes responsible for the metabolism biosynthesis are identified; Finally, the genes are cloned and expressed in heterologous hosts, so as to ensure potentially unlimited production of the metabolites. At present, the bacterial origin of the most abundant sponge metabolite has been established so as to ensure a potentially unlimited production of the metabolites. At present, the bacterial origin of the most abundant sponge metabolite has been established so as to ensure a potentially unlimited production of the metabolites. At present, the bacterial origin of the most abundant sponge metabolite has been establishedPlakortis simplex , the plakortin, and the identification of its biosynthetic genes is underway. More recently, the research activity of Dr. Emperor addressed the examination of the chemical composition of Ascidia in the Mediterranean Sea in search of new pharmacologically active substances. The research activity of Dr. Emperor is documented by 32 publications in widely distributed international journals and 30 communications at national and international conferences.