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Marinelli Luciana

Professor of Pharmaceutical Chemistry
Department of Pharmacy
University Federico II
Italy

Biography

Ph.D. in Pharmaceutical Sciences, Fifteenth cycle, at the University of Naples Federico II, PhD thesis "Molecular modeling of avb3 Integrin antagonists" from 01-11-2000 to 04-03-2003 Research Certificate at the Department of Pharmaceutical and Toxicology Chemistry from 01-06-2003 to 18-01-2005 Component of the University Work Group (University of Naples Federico II) for ISI WoS VQR Transition Threshold Calculation 2004-2010. from 07-03-2012 to 30-03-2012 Member of the Department of Pharmacy of the University of Naples "Federico II". from 01-01-2013 to 30-12-2015 Since 2015 she is a Member of the RESEARCH COMMISSION set up by the Department of Pharmacy of the University of Naples "Federico II" from 01-01-2015 to today

Research Interest

Dr. Marinelli's research is part of the field of pharmaceutical chemistry and in particular in computational chemistry. To date, Luciana Marinelli has dealt with the definition of the three-dimensional structure of proteins and peptides of pharmaceutical interest through the most modern computational techniques (DG, MD, ab initio), the definition of binding methods of organic ligands or peptide to targets of pharmaceutical interest (molecular docking), design or retrieval of new drugs based on known receptor or ligand knowledge through virtual screening calculations (VS).

Publications

  • Chemical modifications in the seed region of miRNAs 221/222 increase the silencing performances in gastrointestinal stromal tumor cells

  • Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells

  • A Healthy Balance of Plasma Cholesterol by a Novel Annurca Apple-Based Nutraceutical Formulation: Results of a Randomized Trial

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