Mayol Laura

Biography

In 2004 he holds a Ph.D. in Chemical Engineering, Materials and Production at Biomateriali (cycle XVII) at the University of Naples Federico II, discussing a thesis titled "Rheological properties of soft natural tissues and their biomimetic substitutes "(Supervisor Prof. Luigi Ambrosio, coordinator Prof. Nino Grizzuti). In 2001 she graduated from the University of Naples, Federico II (110/110) in Materials Engineering (110/110).

Research Interest

Dr. Mayol's scientific activity was essentially carried out in two lines of research. The first is focused on the design of bio-mimetic materials of soft natural tissues and is based in particular on the study of the relationships between their macroscopic properties and the molecular structure through rheological and transport properties analysis. Possible biomedical applications involve the replacement and / or repair of a natural tissue by implanting and / or direct injection of a biomaterial into the human body or, alternatively, using the latter as a three-dimensional support ( scaffold ) able to promote the growth of new cells, and thus again tissue identical to the natural ( tissue engineering ). The second line of research aims at the design and development of polymeric, lipidic or zeolite materials for local and systemic drug delivery. Such systems should be properly designed to ensure adequate time to stay on the drug at the site of administration and a check on its release kinetics. For drugs with limited water solubility, the use of cyclodextrins such as water solubilizing agents and release kinetics modulators is also studied. This approach is of particular interest in the transmucosal delivery of peptides and proteins whose unfavorable pharmacokinetic profile poses strong limitations to the use of non-invasive administration routes.