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Mitidieri Emma

Pharmacology Researcher
Department of Pharmacy
University Federico II
Italy

Biography

2001: Scientific Maturity 2001: English Language Diploma at Trinity College 2001-2006: Student at the Faculty of Pharmacy, Ph.D. in Pharmaceutical Chemistry and Technology at the University of Naples "Federico II" 2005-2006: Internal student at the Department of Experimental Pharmacology at the Faculty of Pharmacy of the University of Naples "Federico II" 2006: Ph.D. in Pharmaceutical Chemistry and Technology with voting 110/110

Research Interest

Dr. Mitidieri's research activity focused on the study of endogenous gas transmitters, such as nitrogen monoxide and hydrogen sulphide, in the pathophysiologic mechanisms of the genito-urinary system. The doctor studied the vascular reactivity of the human cavernous body, obtained following surgery for sex change, and in particular evaluated the role of hydrogen sulphide and nitrogen oxide in erection. In addition, Dr. Mitidieri is expert in measuring intracavernosa pressure in anesthetized rats. The role of sulfuric acid has been evaluated in the human bladder using tissues taken during prostatectomy surgery. The doctor also studied the involvement of the sulphidic acid pathway in in vivo studies in inflammatory models such as edema in the paw's jaw and in ex vivo studies on platelet activity. Dr. Mitidieri is experienced in measuring systemic pressure in rats in vivo in a crudely and obfusive manner. Another topic of Dr. Mitidieri's interest concerns cardiovascular disease associated with endothelial dysfunction, including hypertension, diabetes, and carotid arterial pressure overhead caused by aortic transverse stenosis. He also has extensive experience in molecular biology (western blot, immunoenzymatic dosage and immunoprecipitation). Dr. Mitidieri also has experience in ex vivo studies on human cavernous body caverns and human bladder, aorta and carotid ring, ileus and fasting, mesenteric isolation and perfusion, and platelet aggregation.

Publications

  • Hydrogen sulfide compensates nitric oxide deficiency in murine corpus cavernosum

  • Vascular effects of linagliptin in non-obese diabetic mice are glucose-independent and involve positive modulation of the endothelial nitric oxide synthase (eNOS)/caveolin-1 (CAV-1) pathway.

  • Attività antinfiammatoria dei Glucocorticoidi: nuovi mediatori e regolazione dell'attività dei linfociti T

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