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Perissutti Elisa

Professor of Pharmaceutical Chemistry
Department of Pharmacy
University Federico II
Italy

Biography

In service at the Faculty of Pharmacy (today Department of Pharmacy) since 06 December 1990, as a Researcher. Starting from November 2002 he is in the service of Professor Associate - disciplinary subordinate discipline CHIM / 08 Academic and Academic positions - Secretary of the Council of Class L-29; - Chairman of the CDL's Self-Assessment Group (GAV) in "Quality Control"; President of the Commission for Traineeships in the Quality Control Board; Coordinator of the 2nd level Master in "REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) and Associated Regulations for the Management of Chemical Substances" - established at the Department of Pharmacy - University of Naples Federico II until 2015 ; Component of the CTO of the School of Specialization in "Evaluation and Management of Chemical Risk"; Member of the Doctoral School of Ph.D. Research in "Medicine Science" established at the Faculty of Pharmacy of the University of Naples "Federico II" from 2007 to 2012. PhD Doctorate in Pharmacy Research PhD

Research Interest

Prof. Elisa Perissutti's research activity is aimed at synthesizing and studying the structure-activity relationships of serotonin and analgesic-anti-inflammatory heterocyclic and peptide compounds. At the same time, a series of studies on the cardiovascular system were conducted by synthesis of 1,4-benzoxazine and peptidomimetic compounds. Part of these studies allowed us to deepen the role played by protease-activated receptors (PARs) in some onclogic and cardiovascular pathophysiological processes. Finally, synthetic studies have been undertaken aimed at optimizing the synthesis of bioactive molecules by applying innovative chemistry based on the use of microwaves and the principles of combinatorial chemistry. In particular, it has been investigated, by means of electromagnetic microwave heating, the possibility of making the synthesis of biologically active heterocyclic and peptide compounds more rapid but also more convenient. The research activity is carried out in 93 journals in international magazines with impact factor, to which numerous communications to congresses and conferences are to be added.

Publications

  • Synthesis and in Vitro Screening of New Series of 2,6-Dipeptidyl-anthraquinones: Influence of Side Chain Length on HIV-1 Nucleocapsid Inhibitors

  • Level, potential sources of polycyclic aromatic hydrocarbons (PAHs) in particulate matter (PM10) in Naples

  • Synthesis of Arylpiperazine Derivatives as Protease Activated Receptor 1 Antagonists and Their Evaluation as Antiproliferative Agents

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