Zampella Angela

Biography

In 1986 he achieved scientific maturity with the vote of 60-60. On July 23, 1991 he graduated in Pharmaceutical Chemistry and Technology by declaring his 110th grading and praise by discussing a thesis in Organic Chemistry titled 'Isolation and Structural Characterization of Two Triterpenoid Oligoglycosides from Sponge Erylus sp. using NMR Two-dimensional Spectroscopy ', Prof. Luigi Minale. In December 1991 he was awarded the Ph.D. in Pharmacolinguistic Active Substances-7 'three-year cycle' at the Faculty of Pharmacy of the University of Naples. From May 1, 1994 to October 31, 1994, he has been researching at the Institute of Research of the Chimie of Substances Naturelles at the CNRS of Gif-sur-Yvette (Fancia). During the period from 1 December 1994 to 28 February 1995 and 29 February to 31 March 1996 he has been awarded two contracts of scientific collaboration working at the Department of Natural Chemistry of the University of Naples 'Federico II' on the Extraction and Isolation of Bioactive Metabolites by Spugne. In 1995 he was the winner of a scholarship of the National Research Council (Finalized Chemistry Project Ending) of 10 months. For the academic year 1995-96 contract professor, the teaching of Organic Chemistry Laboratory I for the Chemical Degree Course of the Faculty of Science MM.FF.NN. of the University of Salerno. Biennial post-doctoral bursary (1996-1998). In September 1998 he was the winner of the C05X disciplinary disciplinary competition at the Faculty of Pharmacy of Federico II University in Naples. Since 2002 she has been a professor in the same Faculty. Since December 2016 he is an ordinary professor at the Department of Pharmacy TEACHINGS Academic Year 2002-2003 Biomolecule spectroscopic analysis for the degree in Chemistry and Pharmaceutical Technology (institutional task, 10 CFUs). Physical Methods in Organic Chemistry for the Biotechnology Degree Course - Pharmaceutical Address of the Faculty of Biotechnical Sciences (6 CFU, II semester). Organic Chemistry Laboratory for the Campus of Specialization at the Teaching-Natural Science Course (20 hours). Academic Year 2003-2004 Biomolecule spectroscopic analysis for Bachelor of Science in Pharmaceutical Chemistry and Technology (institutional task, 10 CFU). Physical Methods in Organic Chemistry for Biotechnology Degree - Pharmaceutical Address of the Faculty of Biotechnical Sciences (6 CFU, II semester). Organic Chemistry Laboratory for the Campus of Specialization at the Teaching-Natural Science Course (20 hours). Academic Year 2004-2005 Biomolecule spectroscopic analysis of the degree program in Chemistry and Pharmaceutical Technology (institutional task, 10 CFUs). Biomolecule spectroscopic analysis for the specialist degree in Biotechnology of the Faculty of Biotechnical Sciences (6 CFU, II semester). Organic Chemistry Laboratory for the Campus School of Specialization at the Teaching-Natural Science Course (20 hours)) Academic Year 2005-2006 Biomolecule spectroscopic analysis of the degree program in Chemistry and Pharmaceutical Technology (institutional task, 10 CFUs) Academic year 2006-2010 Organic Chemistry 1 for the Degree in CTF (Institutional Assignment, 10 CFUs) Academic year 2010-to date Spectroscopic Methods in Organic Chemistry for the Degree in CTF (Institutional Tasks, 10 CFUs)

Research Interest

Study of pharmacologically active secondary metabolites isolated from marine organisms - Isolation, structural characterization by NMR techniques, mass spectrometry, circular dichroism -Semisyntesis and total synthesis of cyclic peptides, macrolides and steroid nuclei · Solving problems of a stereochemical nature -Configuration of ribosomal and non-ribosomal amino acids - Relative and absolute configuration of polycatic units Enantioselective synthesis of amino acidic units and complex carbonaceous skeletons · Screening of marine and terrestrial organisms for the detection of new therapeutic approaches - Identification of natural substances such as nuclear receptor ligands and membrane receptors -Design, design and synthesis of enhanced analogs in pharmacological activity Medicinal chemistry -Total total -Drug discovery for the treatment of orphan human diseases such as fibrosis, cirrhosis, inflammatory bowel and liver disorders -Drug discovery for metabolic dis-adjustment therapy: obesity, atherosclerosis and diabetes.