Giuseppe Fracchiolla
Researcher
Department of Pharmacy
University of Aldo Moro
Italy
Biography
Giuseppe Fracchiolla, is working as researcher in the Department of Pharmacy, University of Aldo Moro.
Research Interest
Pharmaceutical sciences, Medical sciences
Publications
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Montanari R, Saccoccia F, Scotti E, Crestani M, Godio C, Gilardi F, Loiodice F, Fracchiolla G, Laghezza A, Tortorella P, Lavecchia A. Crystal structure of the peroxisome proliferator-activated receptor γ (PPARγ) ligand binding domain complexed with a novel partial agonist: a new region of the hydrophobic pocket could be exploited for drug design. Journal of medicinal chemistry. 2008 Nov 18;51(24):7768-76.
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Pochetti G, Godio C, Mitro N, Caruso D, Galmozzi A, Scurati S, Loiodice F, Fracchiolla G, Tortorella P, Laghezza A, Lavecchia A. Insights into the Mechanism of Partial Agonism CRYSTAL STRUCTURES OF THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR γ LIGAND-BINDING DOMAIN IN THE COMPLEX WITH TWO ENANTIOMERIC LIGANDS. Journal of Biological Chemistry. 2007 Jun 8;282(23):17314-24.