Valentina Onnis

Biography

1989: Degree in Pharmaceutical Chemistry and Technology. 1990: Degree in Pharmacy. 1991-2001: Graduated technician at the University of Cagliari. 2001-2011: Certified Researcher of the Department of Toxicology, Pharmaceutical Chemistry Section, University of Cagliari. 2011-2012: Researcher of the Department of Pharmaceutical Chemistry, University of Cagliari 2012-2014: Researcher of the Department of Life and Environmental Sciences, Department of Pharmaceutical Sciences, Pharmacology and Nutrition, University of Cagliari 2015-: Professor of Second Life at the Department of Life and Environmental Sciences, Department of Pharmaceutical Sciences, Pharmacology and Nutrition, University of Cagliari 2004-2010: Member of the College of PhD students of Pharmaceutical Sciences, University of Ferrara. 2006-2011: Member of the College of Teachers of the Doctoral School of Toxicology, University of Cagliari. 2011-2016: Member of the College of PhD students in Chemical Sciences and Pharmaceutical Sciences, Ph.D. in Pharmaceutical Sciences and Technologies, University of Cagliari. 2013-: Member of the College of PhD students in Life Sciences, Environment and Medicine, University of Cagliari. 2007-2012: Delegate of the Presidency in the Pharmacy Faculty Guidance Commission. 2012-: Delegate of the Coordinators of Class L-29 and LM-13 Councils in the Guidance Committee. 2010-2012: a member of the Integrated Academic Senate of the University of Cagliari. 2012-2015: member of the Board of the Faculty of Biology and Pharmacy. 2015-: Component of the Academic Senate of the University of Cagliari. Didactic activity: Professor of Pharmaceutical Chemistry and Toxicology 2 from AA 2011-2012 (Ph.D. in Chemistry and Pharmaceutical Technology, University of Cagliari). Lecturer of Medicines Analysis 1 from the AA 2015-2016 (Pharmacy Degree Course, University of Cagliari) Pharmacology Analyst 1 from AA 2001-2002 to AA 2009-2010 and from AA 2011-12 to AA 2014-2015 (PhD in Pharmaceutical Chemistry and Technology, University of Cagliari). Società Scientifica: Member of: Società Chimica Italiana (1990-), from 2002 to 2007 and from 2011 to 2016 was a member of the Board of Directors of the Sardegna section of the same company. He is author of about 90 extensible publications in international journals. The research is related to the design, development of synthetic methodologies for heterologous biological activity systems, study of the structure structures of molecules with antitumor, analgesic and antimicrobial activity of enzyme inhibitors. Collaborations in progress with other research groups: National Cancer Institutes (Bethesda, MD, USA); Prof. Christopher Fowler, Department of Pharmacology and Clinical Neuroscience, Umea University, Sweden; Dr. Aron Lichtman Department of Pharmacology, Virginia Commonwealth University, Richmond (USA). English version Education 1989: master degree in Pharmaceutical Chemistry and Technology at the University of Cagliari. 1990: Master in Pharmacy at the University of Cagliari. Employment: 1991-2001: Graduated technician at the University of Cagliari. 2001-2014: Medicinal Chemistry Assistant Professor (University of Cagliari). From 2015: Medicinal Chemistry Associate Professor (Department of Life and Environmental Sciences, Unit of Pharmaceutical, Pharmacological and Nutraceutical Sciences, University of Cagliari) 2004-2010: Member of the PhD Program in Pharmaceutical Sciences (University of Ferrara). 2006-2011: Member of the PhD Program in Toxicology (University of Cagliari). 2011-2016: Member of the PhD Program in Pharmaceutical Sciences and Technologies (University of Cagliari) 2013-: Member, Board of the PhD program in Life, Environmental and Drug Sciences (University of Cagliari) Teaching From 2011: Professor, Medicinal Chemistry (School of Biology and Pharmacy, University of Cagliari) From 2001: Professor, Drug Analisys (School of Pharmacy, University of Cagliari)

Research Interest

Summary design and study of activity structure relationships: - pyrrolcarbothioamidic, bispyridylmethane, thioxopyridine, oxopyridine, 2,4-dioxopyridine, dicianopyridine, trifluoromethylpyridine, diaminopirazole, anthranilic and transition metal complex with acetamidrazone and pyrimidine derivatives having antitumor activity; - pyrrole derivatives, imidazoles, isotiazoles having antibacterial activity; - S-alkylchilothiosemicarbazone and isonicotinoylhydrazone derivatives having antituberculous activity; - pyrimidine and triazine derivatives having agonist or antagonist activity on prokineticin receptors; - trifluoromethylpyridine derivatives and heterocyclic amides of hepuprofen having analgesic activity; - condensation derivatives between classical NSAIDs and polyazoteroic heterogeneous compounds such as FAAH enzyme inhibitors.