Alberto Brandi

Biography

Alberto Brandi was born in Florence on January 21, 1951; 1964-69 Classic Maturity. 1969-75 Degree Course in Chemistry, University of Florence. 1975 Degree in Chemistry with 110/110. Title of thesis "Preparation and Polymerization of Acetonitrile Oxide" (Prof. Francesco De Sarlo). 1975-77 Leverage Military Service with Complement Subordinate Degree. 1977-78 Annual teaching assignment at Middle and Upper State Schools. 1978 CNR Scholarship at the Center for Chemistry and the Structure of Eterocyclic Compounds and Their Applications, CNR, University of Florence. 1980 University Researcher Confirmed at the Faculty of Mathematical Physics and Natural Sciences at the University of Florence. 1982-84 NATO Scholarship, University of Wisconsin-Madison, Madison (USA), Prof. Barry M. Trost. 1987 Associate Professor at the Faculty of Mathematical Physics and Natural Sciences at the University of Basilicata (PZ). 1990 Transfer to the Chair of Organic Chemistry, Faculty of Mathematical Physics and Natural Sciences at the University of Florence 1994 Ordinary Professor of Organic Chemistry, Faculty of Mathematical Physics and Natural Sciences, University of Florence.

Research Interest

The most important themes of the researches relate to 1,3-dipolar nitron cycloadditions and their applications in the synthesis of natural compounds, aza-eterocycles and aza-analogs of natural compounds. The stereoselective synthesis of compounds of biological interest such as: glycosidase inhibitors imminosoccharides, amino acids, b-lattami, DNA cleaving agents. Synthesis of peptidomimetics and peptide synthesis. Spirocyclopropanic Heterocyclic Chemistry. Synthesis of organic materials with antennas or gelatinous properties, and functionalized nanomaterials.Among the most important findings of the research is the development of an original nitrogen synthesis synthesis methodology through the thermal transposition of spirocyclopropanoisoxazolidine (Brandi-Guarna reaction), and the development of a class of pyrrolidinic polyoxydrylated nitrides for the synthesis of alkaloids and mimetics of sugars.