Chiara Sassoli

Biography

Born in Arezzo on June 11, 1974 1993 Diploma of Scientific Maturity - Academic High School F. Redi of Arezzo - Voting 57/60. Enrollment in the Degree Course in Biological Sciences - Faculty of Mathematical, Physical and Natural Sciences - University of Florence. 1999 Degree in Biological Sciences - University of Florence Studies - 110/110 and praise (thesis titled "Immunoysthemic analysis of the immune system of the skin and oral mucosa: a difficult compromise between morphology and immunoreactivity" (rapporteur Prof. Paolo Romagnoli, Histology Section, Department of Anatomy, Histology and Legal Medicine) From 1999 to 2000 Practical internship at the Department of Animal and Genetics Biology and the Department of Anatomy of the Department of Anatomy, Histology and Legal Medicine of the University of Florence October 2000-February 2001 Guest Researcher at the Blanchette Rockefeller Neurosciences Institute of the Johns Hopkins University-Gaithersburg-MD-USA (Scientific Director Dr. Daniel L. Alkon) 2001 Enrollment to the profession of Biologist April - June 2001 Co-ordination in a research project titled "Cell cultures aimed at evaluating the inhibition of melatonin neoplastic growth" (Assoc. Fondi Prof. Bruno Neri, Department of Internal Medicine, University of Florence) 1/07 / 2001- 31/12/2001 A scholarship banned by the Florence Savings Bank for the implementation of a project entitled "Role of Neuronal Antigens Hu in Memory: RNA Stabilization by HuC and HuD as a possible molecular basis of learning at the Department of Anatomy, Histology and Legal Medicine of the University of Florence 1/01 / 2002-31 / 12/2004 Doctoral Program in Morphology and Human Morphology at the Department of Anatomy, Histology and Legal Medicine of the University of Florence 6/05/2005 Completion of the Ph.D. title by submitting a final dissertation titled "Cytoskeleton Remodeling and its implications for the function and development of undifferentiated skeletal muscle cells". 1/02 / 2005-31 / 01/2006 Scholarship (research agreement between the Department of Anatomy, Histology and Legal Medicine of the University of Florence and the firm Sigma Tau-Industrie Pharmaceuticals Riunite SpA - Project Prof. Lucia Formigli) for the study "Histologic study on the protective effect of acetyl-L-carnitine (ALCAR) compared to Gabapentin treatment on rats with various neuropathies" to be performed at the Department of Anatomy of the Department of Anatomy, Histology and Legal Medicine of the University of Florence. 1/07 / 2006-30 / 06/2008 Research grant at the Department of Anatomy of the Department of Anatomy, Histology and Legal Medicine of the University of Florence for the realization of the research entitled "Muscular Sports Injury: Possible Strategies for the prevention of damage and functional recovery

Research Interest

Morpho-functional and biochemical characterization of myoblastic cells, with particular reference to the mechanisms involved in the skeletal muscle differentiation process and the role played by bioactive lipids (sphingosine 1-phosphate) on this process. The role of bone marrow stenosis / stem cells (MSCs) isolated from bone marrow in the skeletal muscular regeneration process: study of molecular and cellular mechanisms that regulate the interaction between MSC and myoblastic skeletal cells. Characterization of cardiac progenitor cells, analysis of the effects of the relassin hormone on such cells and the study of cellular and molecular interactions that these cardiac precursors establish with MSC cells to evaluate the potential of stem cells on cardiac regeneration. Study of the effects of Low Level Laser Therapy (LLLT) on the proliferation and differentiation of various cell types of the oral micro-environment and MSC cells in order to identify new therapeutic strategies for bone regeneration in patients with periodontal disease . Further studies of interest: Psychomotority and coordination skills of pre-school children. Correlation between Body Mass Index (BMI) and waist circumference in school age children. Study of the role of ABC proteins in resistance to chemotherapeutic drugs of certain types of cancer cells. She is a member of the Italian Society of Anatomy and Histology (SIAI).